Spectrum of mycobacterial infections: Tuberculosis and mycobacterium other than tuberculosis in dialysis patients

Anna Basok, Marina Vorobiov, Boris Rogachev, Luna Avnon, David Tovbin, Michael Hausmann, Natalya Belenko, Moshe Zlotnik, Alla Shnaider

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Background: Patients with end-stage renal disease are at high risk of mycobacterial infection. Objectives: To analyze the difficulties in reaching an accurate diagnosis of tuberculosis in dialysis patients. Methdos: We conducted a retrospective follow-up of patients who attended our peritoneal and hemodialysis units during the 10 year period 1995-2005. Results: Our dialysis unit diagnosed 10 cases of tuberculosis caused by Mycobacterium tuberculosis and 9 cases of Mycobacterium other than tuberculosis. In the former group, five patients had Mycobacterium in the sputum, which was diagnosed by intraabdominal mass biopsy in one, culture of the gastric juices in one, and pleural fluid culture or pleural biopsy in three. One of these patients was suffering from pleural TB as well as Potts disease. Of the patients with Mycobacterium other than tuberculosis, five were diagnosed by sputum cultures, three by urine cultures and one in peritoneal fluid. Differences in treatment and outcome were also reviewed. Conclusions: The diagnosis of TB in dialysis patients should be approached with a high index of suspicion. It is clear that extensive diagnostic procedures are required to ensure an accurate diagnosis of the disease. Tuberculosis incurs a significant added burden due to the need for isolation of infected patients within the dialysis unit. Treatment of patients with Mycobacterium other than tuberculosis should be addressed individually.

Original languageEnglish
Pages (from-to)448-451
Number of pages4
JournalIsrael Medical Association Journal
Volume9
Issue number6
StatePublished - 1 Jun 2007
Externally publishedYes

Keywords

  • Dialysis
  • Extra-pulmonary
  • Mycobacterium
  • Mycobacterium other than TB
  • Tuberculosis

ASJC Scopus subject areas

  • Medicine (all)

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