Spermatogenesis and reproductive performance following human accidental exposure to bromine vapor

Gad Potashnik, Rafael Carel, Ilana Belmaker, Mordechai Levine

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    5 Scopus citations


    The present study was undertaken to evaluate spermatogenesis and reproductive performance among 8 men and their spouses following accidental exposure to bromine vapor. Of the three cases with oligo-terato-asthenozoospermia (OTA), one had been diagnosed prior to and unrelated to the event. Mild OTA and unimpaired reproductive performance characterized the other two cases. Plasma levels of the follicle stimulating hormone and luteinizing hormone were normal in all men. One first-trimester abortion and one late abortion (due to chorioammionitis) occured among the 5 pregnancies conceived shortly after the accident. Results of the present study suggest a mild degree of spermatogenic suppression and impaired reproductive performance following paternal exposure to bromine vapor during the above described accident. However, due to the small size of the study cohort, a confidential cause-result linkage could not be established.

    Original languageEnglish
    Pages (from-to)171-174
    Number of pages4
    JournalReproductive Toxicology
    Issue number2
    StatePublished - 1 Jan 1992


    • bromine
    • pregnancy outcome
    • spermatogenesis
    • testes

    ASJC Scopus subject areas

    • Toxicology


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