Splenic rupture in chronic lymphoid disorders: Possible role of opportunistic infections

Gilles Lugassy, Moshe Sternfeld, Joseph Van Der Wald, Beatriz Liftschitz-Mercer, Emmanuel Nir, Alain Berrebi

Research output: Contribution to journalArticlepeer-review


Two patients with lymphoproliferative disorders, one with chronic lymphocytic leukemia and the other hairy cell leukemia, developed spontaneous rupture of the spleen during the course of their disease. In both cases, this rare complication occurred during systemic atypical infections with Salmonella Dublin and Candida tropicalis respectively. We suggest that severe infection may sometimes play a decisive role in the development of the splenic rupture in some patients who have splenomegaly due to these disorders.

Original languageEnglish
Pages (from-to)135-138
Number of pages4
JournalLeukemia and Lymphoma
Issue number2
StatePublished - 1 Jan 1990
Externally publishedYes


  • Candida tropicalis
  • Chronic lymphocytic leukemia
  • Hairy cell leukemia
  • Salmonella Dublin
  • Splenic rupture

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research


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