Cough is a disturbing adverse effect of angiotensin-converting enzyme (ACE) inhibitors. Its incidence was found to be very low in postmarketing surveillance studies, but much higher (up to 19%) in studies specifically designed to detect it.1-4 Cough was reported to be the leading cause for discontinuation of ACE inhibitors.1 It is usually persistent and dry, and occasionally may be cause vomiting. It is typically accompanied by a tickling sensation in the throat and rapidly disappears after discontinuation of ACE inhibitors. The exact mechanism of this adverse effect is unknown. The purpose of this report is to describe the patterns of cough induced by ACE inhibitors, emphasizing 3 new patterns in which cough spontaneously disappears permanently or intermittently.
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine