Abstract
NCLX, the mitochondrial Na+/Ca2+ transporter is a key player in Ca2+ signaling. However, its role in Na+ signaling is poorly understood. In this review we focus on Na+ signaling by NCLX, and discuss recent physiological and pathophysiological roles attributed to the Na+ influx into mitochondria.
Original language | English |
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Article number | 102416 |
Journal | Cell Calcium |
Volume | 97 |
DOIs | |
State | Published - 1 Jul 2021 |
Keywords
- Hypoxia
- Ischemia
- Mitochondrial Ca efflux
- NCLX
- Na signaling
ASJC Scopus subject areas
- Physiology
- Molecular Biology
- Cell Biology