Squamous cell carcinoma of the renal pelvis with sarcomalike stroma: A light and electron microscopic study with immunohistochemical analysis

Jed Goldstein, Marta Mozes, Leonid Lismer, Israel Levin

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Primary neoplasms of the renal pelvis are rare. Most are malignant, and most of these are transitional cell carcinomas. We report the unusual occurrence of a squamous cell carcinoma with sarcomatoid stroma arising from the renal pelvic mucosa in a patient with renal lithiasis. Immunohistochemical stains for keratin intermediate filaments failed to demonstrate their presence in the spindle cell portion of the tumor. Transmission electron microscopic study did not reveal structures of an epithelial nature in these same cells. Our findings support the contention that the spindle cells of the stroma are not squamous in nature, but represent either a reactive or a neoplastic transformation of these underlying stromal elements.

Original languageEnglish
Pages (from-to)188-192
Number of pages5
JournalJournal of Surgical Oncology
Volume36
Issue number3
DOIs
StatePublished - 1 Jan 1987
Externally publishedYes

Keywords

  • pseudosarcoma
  • sarcomatoid squamous cell carcinoma

ASJC Scopus subject areas

  • Surgery
  • Oncology

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