Stop GnRH-agonist/GnRH-antagonist protocol: a different insight on ovarian stimulation for IVF

Raoul Orvieto

doi:10.1186/s12958-023-01069-7

Stop GnRH-agonist/GnRH-antagonist protocol: a different insight on ovarian stimulation for IVF

Raoul Orvieto

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

Ovarian stimulation (OS) is one of the key factors in the success of in vitro fertilization-embryo transfer (IVF-ET), by enabling the recruitment of numerous healthy fertilizable oocytes and, thereby, multiple embryos. The Stop GnRH-agonist/GnRH-antagonist (GnRH-ag/GnRH-ant), which offers all the advantages of using long suppressive GnRH-ag, with GnRH-ant, is in my opinion a valuable addition to the armamentarium of OS protocols. It allows cycle programming, better follicular synchronization and offers successful outcome in a variety of challenging cases such as poor responders, Poseidon group 4 poor prognosis patients, those with elevated peak progesterone (P) serum levels, poor embryo quality or repeated IVF failures.

Original language	English
Article number	13
Journal	Reproductive Biology and Endocrinology
Volume	21
Issue number	1
DOIs	https://doi.org/10.1186/s12958-023-01069-7
State	Published - 1 Dec 2023
Externally published	Yes

ASJC Scopus subject areas

Reproductive Medicine
Endocrinology
Obstetrics and Gynecology
Developmental Biology

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10.1186/s12958-023-01069-7

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title = "Stop GnRH-agonist/GnRH-antagonist protocol: a different insight on ovarian stimulation for IVF",

abstract = "Ovarian stimulation (OS) is one of the key factors in the success of in vitro fertilization-embryo transfer (IVF-ET), by enabling the recruitment of numerous healthy fertilizable oocytes and, thereby, multiple embryos. The Stop GnRH-agonist/GnRH-antagonist (GnRH-ag/GnRH-ant), which offers all the advantages of using long suppressive GnRH-ag, with GnRH-ant, is in my opinion a valuable addition to the armamentarium of OS protocols. It allows cycle programming, better follicular synchronization and offers successful outcome in a variety of challenging cases such as poor responders, Poseidon group 4 poor prognosis patients, those with elevated peak progesterone (P) serum levels, poor embryo quality or repeated IVF failures.",

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AB - Ovarian stimulation (OS) is one of the key factors in the success of in vitro fertilization-embryo transfer (IVF-ET), by enabling the recruitment of numerous healthy fertilizable oocytes and, thereby, multiple embryos. The Stop GnRH-agonist/GnRH-antagonist (GnRH-ag/GnRH-ant), which offers all the advantages of using long suppressive GnRH-ag, with GnRH-ant, is in my opinion a valuable addition to the armamentarium of OS protocols. It allows cycle programming, better follicular synchronization and offers successful outcome in a variety of challenging cases such as poor responders, Poseidon group 4 poor prognosis patients, those with elevated peak progesterone (P) serum levels, poor embryo quality or repeated IVF failures.

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Stop GnRH-agonist/GnRH-antagonist protocol: a different insight on ovarian stimulation for IVF

Abstract

ASJC Scopus subject areas

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