Streptococcus pneumoniae nasopharyngeal colonization in children in brasov, central romania: High antibiotic resistance and coverage by conjugate vaccines

Oana Falup-Pecurariu, Laura Bleotu, Cristina Zavarache, Nechama Peled, Oana Anton, Michaela Robu, Cristian Falup-Pecurariu, Liliana Rogozea, Nurith Porat, David Greenberg, Ron Dagan, Eugene Leibovitz

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

We report high colonization rates among 400 healthy infants and children, and moderate (66%) coverage by PCV7 and PCV10, with a superior (80%) PCV13 coverage. Most frequent serotypes were 23F, 6B, 19F, and 14. Resistance to penicillin, ceftriaxone, erythromycin, and trimethoprim/sulfamethoxazole was 83%, 18%, 62%, and 66%, respectively. 67% isolates were multidrug resistant. Pneumococcal conjugate vaccines covered 80% to 93% of multidrug resistant isolates.

Original languageEnglish
Pages (from-to)76-78
Number of pages3
JournalPediatric Infectious Disease Journal
Volume30
Issue number1
DOIs
StatePublished - 1 Jan 2011

Keywords

  • Romania
  • Streptococcus pneumoniae
  • children
  • conjugate vaccines
  • nasopharyngeal colonization

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases

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