TY - JOUR
T1 - Streptococcus pneumoniae nasopharyngeal colonization in children in brasov, central romania
T2 - High antibiotic resistance and coverage by conjugate vaccines
AU - Falup-Pecurariu, Oana
AU - Bleotu, Laura
AU - Zavarache, Cristina
AU - Peled, Nechama
AU - Anton, Oana
AU - Robu, Michaela
AU - Falup-Pecurariu, Cristian
AU - Rogozea, Liliana
AU - Porat, Nurith
AU - Greenberg, David
AU - Dagan, Ron
AU - Leibovitz, Eugene
N1 - Funding Information:
Supported by an ESPID Grant Award.
PY - 2011/1/1
Y1 - 2011/1/1
N2 - We report high colonization rates among 400 healthy infants and children, and moderate (66%) coverage by PCV7 and PCV10, with a superior (80%) PCV13 coverage. Most frequent serotypes were 23F, 6B, 19F, and 14. Resistance to penicillin, ceftriaxone, erythromycin, and trimethoprim/sulfamethoxazole was 83%, 18%, 62%, and 66%, respectively. 67% isolates were multidrug resistant. Pneumococcal conjugate vaccines covered 80% to 93% of multidrug resistant isolates.
AB - We report high colonization rates among 400 healthy infants and children, and moderate (66%) coverage by PCV7 and PCV10, with a superior (80%) PCV13 coverage. Most frequent serotypes were 23F, 6B, 19F, and 14. Resistance to penicillin, ceftriaxone, erythromycin, and trimethoprim/sulfamethoxazole was 83%, 18%, 62%, and 66%, respectively. 67% isolates were multidrug resistant. Pneumococcal conjugate vaccines covered 80% to 93% of multidrug resistant isolates.
KW - Romania
KW - Streptococcus pneumoniae
KW - children
KW - conjugate vaccines
KW - nasopharyngeal colonization
UR - http://www.scopus.com/inward/record.url?scp=78650792091&partnerID=8YFLogxK
U2 - 10.1097/INF.0b013e3181f42bb6
DO - 10.1097/INF.0b013e3181f42bb6
M3 - Article
C2 - 20844463
AN - SCOPUS:78650792091
VL - 30
SP - 76
EP - 78
JO - Pediatric Infectious Disease Journal
JF - Pediatric Infectious Disease Journal
SN - 0891-3668
IS - 1
ER -
