Streptococcus pneumoniae nasopharyngeal colonization in children in brasov, central romania: High antibiotic resistance and coverage by conjugate vaccines

Oana Falup-Pecurariu; Laura Bleotu; Cristina Zavarache; Nechama Peled; Oana Anton; Michaela Robu; Cristian Falup-Pecurariu; Liliana Rogozea; Nurith Porat; David Greenberg; Ron Dagan; Eugene Leibovitz

doi:10.1097/INF.0b013e3181f42bb6

Streptococcus pneumoniae nasopharyngeal colonization in children in brasov, central romania: High antibiotic resistance and coverage by conjugate vaccines

Oana Falup-Pecurariu
, Laura Bleotu
, Cristina Zavarache
, Nechama Peled
, Oana Anton
, Michaela Robu
, Cristian Falup-Pecurariu
, Liliana Rogozea
, Nurith Porat
, David Greenberg
, Ron Dagan
, Eugene Leibovitz

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

We report high colonization rates among 400 healthy infants and children, and moderate (66%) coverage by PCV7 and PCV10, with a superior (80%) PCV13 coverage. Most frequent serotypes were 23F, 6B, 19F, and 14. Resistance to penicillin, ceftriaxone, erythromycin, and trimethoprim/sulfamethoxazole was 83%, 18%, 62%, and 66%, respectively. 67% isolates were multidrug resistant. Pneumococcal conjugate vaccines covered 80% to 93% of multidrug resistant isolates.

Original language	English
Pages (from-to)	76-78
Number of pages	3
Journal	Pediatric Infectious Disease Journal
Volume	30
Issue number	1
DOIs	https://doi.org/10.1097/INF.0b013e3181f42bb6
State	Published - 1 Jan 2011

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Romania
Streptococcus pneumoniae
children
conjugate vaccines
nasopharyngeal colonization

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Microbiology (medical)
Infectious Diseases

Access to Document

10.1097/INF.0b013e3181f42bb6

Cite this

Falup-Pecurariu, O., Bleotu, L., Zavarache, C., Peled, N., Anton, O., Robu, M., Falup-Pecurariu, C., Rogozea, L., Porat, N., Greenberg, D., Dagan, R., & Leibovitz, E. (2011). Streptococcus pneumoniae nasopharyngeal colonization in children in brasov, central romania: High antibiotic resistance and coverage by conjugate vaccines. Pediatric Infectious Disease Journal, 30(1), 76-78. https://doi.org/10.1097/INF.0b013e3181f42bb6

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title = "Streptococcus pneumoniae nasopharyngeal colonization in children in brasov, central romania: High antibiotic resistance and coverage by conjugate vaccines",

abstract = "We report high colonization rates among 400 healthy infants and children, and moderate (66\%) coverage by PCV7 and PCV10, with a superior (80\%) PCV13 coverage. Most frequent serotypes were 23F, 6B, 19F, and 14. Resistance to penicillin, ceftriaxone, erythromycin, and trimethoprim/sulfamethoxazole was 83\%, 18\%, 62\%, and 66\%, respectively. 67\% isolates were multidrug resistant. Pneumococcal conjugate vaccines covered 80\% to 93\% of multidrug resistant isolates.",

keywords = "Romania, Streptococcus pneumoniae, children, conjugate vaccines, nasopharyngeal colonization",

author = "Oana Falup-Pecurariu and Laura Bleotu and Cristina Zavarache and Nechama Peled and Oana Anton and Michaela Robu and Cristian Falup-Pecurariu and Liliana Rogozea and Nurith Porat and David Greenberg and Ron Dagan and Eugene Leibovitz",

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doi = "10.1097/INF.0b013e3181f42bb6",

language = "English",

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journal = "Pediatric Infectious Disease Journal",

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Falup-Pecurariu, O, Bleotu, L, Zavarache, C, Peled, N, Anton, O, Robu, M, Falup-Pecurariu, C, Rogozea, L, Porat, N , Greenberg, D , Dagan, R & Leibovitz, E 2011, 'Streptococcus pneumoniae nasopharyngeal colonization in children in brasov, central romania: High antibiotic resistance and coverage by conjugate vaccines', Pediatric Infectious Disease Journal, vol. 30, no. 1, pp. 76-78. https://doi.org/10.1097/INF.0b013e3181f42bb6

Streptococcus pneumoniae nasopharyngeal colonization in children in brasov, central romania: High antibiotic resistance and coverage by conjugate vaccines. / Falup-Pecurariu, Oana; Bleotu, Laura; Zavarache, Cristina et al.
In: Pediatric Infectious Disease Journal, Vol. 30, No. 1, 01.01.2011, p. 76-78.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Streptococcus pneumoniae nasopharyngeal colonization in children in brasov, central romania

T2 - High antibiotic resistance and coverage by conjugate vaccines

AU - Falup-Pecurariu, Oana

AU - Bleotu, Laura

AU - Zavarache, Cristina

AU - Peled, Nechama

AU - Anton, Oana

AU - Robu, Michaela

AU - Falup-Pecurariu, Cristian

AU - Rogozea, Liliana

AU - Porat, Nurith

AU - Greenberg, David

AU - Dagan, Ron

AU - Leibovitz, Eugene

PY - 2011/1/1

Y1 - 2011/1/1

N2 - We report high colonization rates among 400 healthy infants and children, and moderate (66%) coverage by PCV7 and PCV10, with a superior (80%) PCV13 coverage. Most frequent serotypes were 23F, 6B, 19F, and 14. Resistance to penicillin, ceftriaxone, erythromycin, and trimethoprim/sulfamethoxazole was 83%, 18%, 62%, and 66%, respectively. 67% isolates were multidrug resistant. Pneumococcal conjugate vaccines covered 80% to 93% of multidrug resistant isolates.

AB - We report high colonization rates among 400 healthy infants and children, and moderate (66%) coverage by PCV7 and PCV10, with a superior (80%) PCV13 coverage. Most frequent serotypes were 23F, 6B, 19F, and 14. Resistance to penicillin, ceftriaxone, erythromycin, and trimethoprim/sulfamethoxazole was 83%, 18%, 62%, and 66%, respectively. 67% isolates were multidrug resistant. Pneumococcal conjugate vaccines covered 80% to 93% of multidrug resistant isolates.

KW - Romania

KW - Streptococcus pneumoniae

KW - children

KW - conjugate vaccines

KW - nasopharyngeal colonization

UR - https://www.scopus.com/pages/publications/78650792091

U2 - 10.1097/INF.0b013e3181f42bb6

DO - 10.1097/INF.0b013e3181f42bb6

M3 - Article

AN - SCOPUS:78650792091

SN - 0891-3668

VL - 30

SP - 76

EP - 78

JO - Pediatric Infectious Disease Journal

JF - Pediatric Infectious Disease Journal

IS - 1

ER -

Streptococcus pneumoniae nasopharyngeal colonization in children in brasov, central romania: High antibiotic resistance and coverage by conjugate vaccines

Abstract

UN SDGs

Keywords

ASJC Scopus subject areas

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