TY - JOUR
T1 - Stroke Prevention in Atrial Fibrillation
T2 - The Role of Oral Anticoagulation
AU - Mtwesi, Viwe
AU - Amit, Guy
N1 - Funding Information:
Disclosures: Dr G. Amit received honoraria from Pfizer, Bayer, and a research grant from Servier Canada. Disclosures: Dr G. Amit received honoraria from Pfizer, Bayer, and a research grant from Servier Canada.
Publisher Copyright:
© 2019 Elsevier Inc.
PY - 2019/9/1
Y1 - 2019/9/1
N2 - Oral anticoagulation significantly reduces the risk of stroke in patients with atrial fibrillation (AF), and the decision to initiate therapy is based on assessing the patient's yearly risk of stroke. Although warfarin remains the drug of choice in patients with AF and artificial mechanical valves, the novel anticoagulation agents are becoming the drug of choice for all other patients with AF, because of their efficacy, safety, and ease of use. This article summarizes the current evidence for stroke prevention in AF, including valvular AF, subclinical AF, AF in patients with renal insufficiency, as well as stroke prevention around AF cardioversion.
AB - Oral anticoagulation significantly reduces the risk of stroke in patients with atrial fibrillation (AF), and the decision to initiate therapy is based on assessing the patient's yearly risk of stroke. Although warfarin remains the drug of choice in patients with AF and artificial mechanical valves, the novel anticoagulation agents are becoming the drug of choice for all other patients with AF, because of their efficacy, safety, and ease of use. This article summarizes the current evidence for stroke prevention in AF, including valvular AF, subclinical AF, AF in patients with renal insufficiency, as well as stroke prevention around AF cardioversion.
KW - Anticoagulation
KW - Atrial fibrillation
KW - NOAC
KW - Stroke prevention
KW - Warfarin
UR - http://www.scopus.com/inward/record.url?scp=85069974540&partnerID=8YFLogxK
U2 - 10.1016/j.mcna.2019.05.006
DO - 10.1016/j.mcna.2019.05.006
M3 - Review article
AN - SCOPUS:85069974540
VL - 103
SP - 847
EP - 862
JO - Medical Clinics of North America
JF - Medical Clinics of North America
SN - 0025-7125
IS - 5
ER -