Studies on production and biological potential of prodigiosin by Serratia marcescens

Rahul K. Suryawanshi, Chandrashekhar D. Patil, Hemant P. Borase, Bipinchandra K. Salunke, Satish V. Patil

Research output: Contribution to journalArticlepeer-review

74 Scopus citations


Efficacy of Serratia marcescens for pigment production and biological activity was investigated. Natural substrates like sweet potato, mahua flower extract (Madhuca latifolia L.), and sesam at different concentrations were taken. As a carbon source microorganism favored potato powder was followed by sesam and mannitol, and as nitrogen source casein hydrolysate was followed by yeast and malt extract. The effect of inorganic salts on pigment production was also studied. At final optimized composition of suitable carbon, nitrogen source, and trace materials and at suitable physiological conditions, prodigiosin production was 4.8 g L-1. The isolated pigment showed antimicrobial activity against different pathogenic bacteria and fungi. Extracted pigment was characterized by spectroscopy, Fourier transform infrared (FTIR), and thin layer chromatography (TLC) which confirm production of biological compound prodigiosin. This study suggests that use of sweet potato powder and casein can be a potential alternative bioresource for commercial production of pigment prodigiosin.

Original languageEnglish
Pages (from-to)1209-1221
Number of pages13
JournalApplied Biochemistry and Biotechnology
Issue number5
StatePublished - 1 Jan 2014
Externally publishedYes


  • Optimization
  • Prodigiosin
  • Production
  • Serratia

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology


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