Studies towards total synthesis of borrelidin, regioselective methylation of bis-epoxides and structure determination

Nizar Haddad; Ashraf Brik; Michael Grishko

doi:10.1016/S0040-4039(97)01372-5

Studies towards total synthesis of borrelidin, regioselective methylation of bis-epoxides and structure determination

Nizar Haddad, Ashraf Brik, Michael Grishko

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Regioselective methylation of bis-epoxides 9 were examined. Two examples of high regioselectivity and yield were achieved. Structure determination of the four possible regioisomers provide useful information for structure determination of structurally related flexible molecules.

Original language	English
Pages (from-to)	6079-6082
Number of pages	4
Journal	Tetrahedron Letters
Volume	38
Issue number	34
DOIs	https://doi.org/10.1016/S0040-4039(97)01372-5
State	Published - 1 Aug 1997
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(97)01372-5

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title = "Studies towards total synthesis of borrelidin, regioselective methylation of bis-epoxides and structure determination",

abstract = "Regioselective methylation of bis-epoxides 9 were examined. Two examples of high regioselectivity and yield were achieved. Structure determination of the four possible regioisomers provide useful information for structure determination of structurally related flexible molecules.",

author = "Nizar Haddad and Ashraf Brik and Michael Grishko",

note = "Funding Information: This research was supported by grant No. 95-00222 from the United States-Israel Binational Science Foundation (BSF), Jerusalem, Israel.",

year = "1997",

month = aug,

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doi = "10.1016/S0040-4039(97)01372-5",

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journal = "Tetrahedron Letters",

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T1 - Studies towards total synthesis of borrelidin, regioselective methylation of bis-epoxides and structure determination

AU - Haddad, Nizar

AU - Brik, Ashraf

AU - Grishko, Michael

N1 - Funding Information: This research was supported by grant No. 95-00222 from the United States-Israel Binational Science Foundation (BSF), Jerusalem, Israel.

PY - 1997/8/1

Y1 - 1997/8/1

N2 - Regioselective methylation of bis-epoxides 9 were examined. Two examples of high regioselectivity and yield were achieved. Structure determination of the four possible regioisomers provide useful information for structure determination of structurally related flexible molecules.

AB - Regioselective methylation of bis-epoxides 9 were examined. Two examples of high regioselectivity and yield were achieved. Structure determination of the four possible regioisomers provide useful information for structure determination of structurally related flexible molecules.

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U2 - 10.1016/S0040-4039(97)01372-5

DO - 10.1016/S0040-4039(97)01372-5

M3 - Article

AN - SCOPUS:0030871393

SN - 0040-4039

VL - 38

SP - 6079

EP - 6082

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 34

ER -

Studies towards total synthesis of borrelidin, regioselective methylation of bis-epoxides and structure determination

Abstract

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