Study of urological devices coated with fullerene-like nanoparticles

Ohad Goldbart, Olga Elianov, Dmitry Shumalinsky, Leonid Lobik, Shmuel Cytron, Rita Rosentsveig, H. Daniel Wagner, Reshef Tenne

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Insertion of endoscopes and other medical devices into the human body are ubiquitous, especially among aged males. The applied force for the insertion/extraction of the device from the urethra must overcome endoscope-surface-human-tissue interactions. In daily practice a gel is applied on the endoscope surface, in order to facilitate its entry into the urethra, providing also for local anesthesia. In the present work, a new solid-state lubricant has been added to the gel, in order to reduce the metal-urethra interaction and alleviate the potential damage to the epithelial tissue. For that purpose, a urethra model was designed and fabricated, which allowed a quantitative assessment of the applied force for extraction of the endoscope from a soft polymer-based ring. It is shown that the addition of MoS2 nanoparticles with fullerene-like structure (IF-MoS2) and in particular rhenium-doped nanoparticles (Re:IF-MoS2) to Esracain gel applied on the metal-lead reduced the friction substantially. The Re:IF-MoS 2 showed better results than the undoped fullerene-like nanoparticles and both performed better than the gel alone. The mechanism of friction reduction is attributed to fullerenes' ability to roll and act as a separator between the active parts of the model.

Original languageEnglish
Pages (from-to)8526-8532
Number of pages7
JournalNanoscale
Volume5
Issue number18
DOIs
StatePublished - 21 Sep 2013
Externally publishedYes

ASJC Scopus subject areas

  • Materials Science (all)

Fingerprint

Dive into the research topics of 'Study of urological devices coated with fullerene-like nanoparticles'. Together they form a unique fingerprint.

Cite this