Successful response to docetaxel treatment in recurrent ovarian granulosa cell tumor: A case report

T. Shavit, I. Bruchim, Z. Ben-Harim, A. Fishman

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Background: Ovarian granulosa cell tumor (GCT) is primarily treated surgically. Treatment for advanced or recurrent disease includes primary or adjuvant chemotherapy. Data about the efficacy of treatment with paclitaxel are limited, without data about the role of docetaxel in treating recurrent GCT. Case: A 68-year-old patient with Stage IA ovarian GCT diagnosed ten years earlier, presented with a third episode of recurrent disease. Following the first event of recurrent disease, she underwent a second laparotomy followed by BEP chemotherapy. Because of new liver masses, she was treated with paclitaxel, with complete response. Following diagnosis of new liver lesions, third-line chemotherapy with docetaxel was initiated, resulting in stable disease and a PFI of 24 months. Conclusion: Docetaxel might be a good alternative for treating recurrent GCT.

Original languageEnglish
Pages (from-to)419-420
Number of pages2
JournalEuropean Journal of Gynaecological Oncology
Volume33
Issue number4
StatePublished - 17 Sep 2012
Externally publishedYes

Keywords

  • Docetaxel
  • Granulosa cell tumor

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynecology

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