Sulfasalazine Hepatotoxicity

A. Fich; J. Schwartz; D. Braverman; A. Zifroni; D. Rachmilewitz

doi:10.1111/j.1572-0241.1984.tb05144.x

Sulfasalazine Hepatotoxicity

A. Fich, J. Schwartz, D. Braverman, A. Zifroni, D. Rachmilewitz

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Hepatotoxicity has been recently described as a rare complication of sulfasalazine therapy. Two patients with hepatic damage after sulfasalazine treatment are reported. Liver biopsy performed in one patient revealed granulomatous hepatitis. On rechallenge with 5 aminosalicylic acid enema the second patient developed a hypersensitivity reaction without hepatic involvement.

Original language	English
Pages (from-to)	401-402
Number of pages	2
Journal	American Journal of Gastroenterology
Volume	79
Issue number	5
DOIs	https://doi.org/10.1111/j.1572-0241.1984.tb05144.x
State	Published - 1 Jan 1984
Externally published	Yes

ASJC Scopus subject areas

Hepatology
Gastroenterology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/j.1572-0241.1984.tb05144.x

Cite this

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title = "Sulfasalazine Hepatotoxicity",

abstract = "Hepatotoxicity has been recently described as a rare complication of sulfasalazine therapy. Two patients with hepatic damage after sulfasalazine treatment are reported. Liver biopsy performed in one patient revealed granulomatous hepatitis. On rechallenge with 5 aminosalicylic acid enema the second patient developed a hypersensitivity reaction without hepatic involvement.",

author = "A. Fich and J. Schwartz and D. Braverman and A. Zifroni and D. Rachmilewitz",

year = "1984",

month = jan,

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doi = "10.1111/j.1572-0241.1984.tb05144.x",

language = "English",

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pages = "401--402",

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publisher = "Wolters Kluwer Health",

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TY - JOUR

T1 - Sulfasalazine Hepatotoxicity

AU - Fich, A.

AU - Schwartz, J.

AU - Braverman, D.

AU - Zifroni, A.

AU - Rachmilewitz, D.

PY - 1984/1/1

Y1 - 1984/1/1

N2 - Hepatotoxicity has been recently described as a rare complication of sulfasalazine therapy. Two patients with hepatic damage after sulfasalazine treatment are reported. Liver biopsy performed in one patient revealed granulomatous hepatitis. On rechallenge with 5 aminosalicylic acid enema the second patient developed a hypersensitivity reaction without hepatic involvement.

AB - Hepatotoxicity has been recently described as a rare complication of sulfasalazine therapy. Two patients with hepatic damage after sulfasalazine treatment are reported. Liver biopsy performed in one patient revealed granulomatous hepatitis. On rechallenge with 5 aminosalicylic acid enema the second patient developed a hypersensitivity reaction without hepatic involvement.

UR - http://www.scopus.com/inward/record.url?scp=0021340171&partnerID=8YFLogxK

U2 - 10.1111/j.1572-0241.1984.tb05144.x

DO - 10.1111/j.1572-0241.1984.tb05144.x

M3 - Article

AN - SCOPUS:0021340171

SN - 0002-9270

VL - 79

SP - 401

EP - 402

JO - American Journal of Gastroenterology

JF - American Journal of Gastroenterology

IS - 5

ER -

Sulfasalazine Hepatotoxicity

Abstract

ASJC Scopus subject areas

UN SDGs

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