Sulfasalazine Hepatotoxicity

A. Fich, J. Schwartz, D. Braverman, A. Zifroni, D. Rachmilewitz

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Hepatotoxicity has been recently described as a rare complication of sulfasalazine therapy. Two patients with hepatic damage after sulfasalazine treatment are reported. Liver biopsy performed in one patient revealed granulomatous hepatitis. On rechallenge with 5 aminosalicylic acid enema the second patient developed a hypersensitivity reaction without hepatic involvement.

Original languageEnglish
Pages (from-to)401-402
Number of pages2
JournalAmerican Journal of Gastroenterology
Issue number5
StatePublished - 1 Jan 1984
Externally publishedYes

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


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