The 1H and 13C NMR spectra of some 2-alkyl- and 2,3-dialkyl-1-vinylpyrroles as well as model 1-unsubstituted pyrroles were studied. Alkyi substituents affect electronic structures of the compounds through steric inhibition of p,π-conjugation and π-induction. Correlations of the 13C chemical shifts of the pyrrole ring carbon atoms with the total charge density (CNDO/2) of these atoms are established.
|Number of pages||9|
|State||Published - 1 Jan 1981|
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry