Supportive data on the regulation of GLUT4 activity by 3-O-methyl-D-glucose

Ofer Shamni; Guy Cohen; Arie Gruzman; Hilal Zaid; Amira Klip; Erol Cerasi; Shlomo Sasson

doi:10.1016/j.dib.2017.07.069

Supportive data on the regulation of GLUT4 activity by 3-O-methyl-D-glucose

Ofer Shamni, Guy Cohen, Arie Gruzman, Hilal Zaid, Amira Klip, Erol Cerasi, Shlomo Sasson

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The data presented in this article are related to the research article entitled “Regulation of GLUT4 activity in myotubes by 3-O-methyl-D-glucose” (Shamni et al., 2017) [1]. These data show that the experimental procedures used to analyze the effects of 3-O-methyl-D-glucose (MeGlc) on the rate of hexose transport into myotubes were valid and controlled. The stimulatory effect of MeGlc was limited to glucose transporter 4 (GLUT4) and was independent of ambient glucose and protein synthesis. Cornish-Bowden kinetic analysis of uptake data revealed that MeGlc attenuated indinavir-induced inhibition of hexose transport in a competitive manner.

Original language	English
Pages (from-to)	329-336
Number of pages	8
Journal	Data in Brief
Volume	14
DOIs	https://doi.org/10.1016/j.dib.2017.07.069
State	Published - 1 Oct 2017
Externally published	Yes

Keywords

3-O-methyl glucose
Glucose transporter 4
Indinavir
Intrinsic activity
Myotubes

ASJC Scopus subject areas

General

Access to Document

10.1016/j.dib.2017.07.069

Cite this

@article{15c056dc40144e76adeb5c8c2de091cf,

title = "Supportive data on the regulation of GLUT4 activity by 3-O-methyl-D-glucose",

abstract = "The data presented in this article are related to the research article entitled “Regulation of GLUT4 activity in myotubes by 3-O-methyl-D-glucose” (Shamni et al., 2017) [1]. These data show that the experimental procedures used to analyze the effects of 3-O-methyl-D-glucose (MeGlc) on the rate of hexose transport into myotubes were valid and controlled. The stimulatory effect of MeGlc was limited to glucose transporter 4 (GLUT4) and was independent of ambient glucose and protein synthesis. Cornish-Bowden kinetic analysis of uptake data revealed that MeGlc attenuated indinavir-induced inhibition of hexose transport in a competitive manner.",

keywords = "3-O-methyl glucose, Glucose transporter 4, Indinavir, Intrinsic activity, Myotubes",

author = "Ofer Shamni and Guy Cohen and Arie Gruzman and Hilal Zaid and Amira Klip and Erol Cerasi and Shlomo Sasson",

note = "Publisher Copyright: {\textcopyright} 2017 The Authers",

year = "2017",

month = oct,

day = "1",

doi = "10.1016/j.dib.2017.07.069",

language = "English",

volume = "14",

pages = "329--336",

journal = "Data in Brief",

issn = "2352-3409",

publisher = "Elsevier Inc.",

}

TY - JOUR

T1 - Supportive data on the regulation of GLUT4 activity by 3-O-methyl-D-glucose

AU - Shamni, Ofer

AU - Cohen, Guy

AU - Gruzman, Arie

AU - Zaid, Hilal

AU - Klip, Amira

AU - Cerasi, Erol

AU - Sasson, Shlomo

PY - 2017/10/1

Y1 - 2017/10/1

N2 - The data presented in this article are related to the research article entitled “Regulation of GLUT4 activity in myotubes by 3-O-methyl-D-glucose” (Shamni et al., 2017) [1]. These data show that the experimental procedures used to analyze the effects of 3-O-methyl-D-glucose (MeGlc) on the rate of hexose transport into myotubes were valid and controlled. The stimulatory effect of MeGlc was limited to glucose transporter 4 (GLUT4) and was independent of ambient glucose and protein synthesis. Cornish-Bowden kinetic analysis of uptake data revealed that MeGlc attenuated indinavir-induced inhibition of hexose transport in a competitive manner.

AB - The data presented in this article are related to the research article entitled “Regulation of GLUT4 activity in myotubes by 3-O-methyl-D-glucose” (Shamni et al., 2017) [1]. These data show that the experimental procedures used to analyze the effects of 3-O-methyl-D-glucose (MeGlc) on the rate of hexose transport into myotubes were valid and controlled. The stimulatory effect of MeGlc was limited to glucose transporter 4 (GLUT4) and was independent of ambient glucose and protein synthesis. Cornish-Bowden kinetic analysis of uptake data revealed that MeGlc attenuated indinavir-induced inhibition of hexose transport in a competitive manner.

KW - 3-O-methyl glucose

KW - Glucose transporter 4

KW - Indinavir

KW - Intrinsic activity

KW - Myotubes

UR - http://www.scopus.com/inward/record.url?scp=85026782636&partnerID=8YFLogxK

U2 - 10.1016/j.dib.2017.07.069

DO - 10.1016/j.dib.2017.07.069

M3 - Article

AN - SCOPUS:85026782636

SN - 2352-3409

VL - 14

SP - 329

EP - 336

JO - Data in Brief

JF - Data in Brief

ER -

Supportive data on the regulation of GLUT4 activity by 3-O-methyl-D-glucose

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this