Suppression of ehrlich ascites tumors in mice by minute virus of mice

Esther Guetta; Yosef Graziani; Jacov Tal

doi:10.1093/jnci/76.6.1177

Suppression of ehrlich ascites tumors in mice by minute virus of mice

Esther Guetta, Yosef Graziani, Jacov Tal

Virology

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

Abstract

As a model system to study parvoviral oncosuppression, Ehrlich ascites (EA) cells were injected into the peritoneal cavities of ICR mice, and the effect of im injection of minute virus of mice (MVM) on EA tumor growth was examined. Coinjection with MVM resulted in a dramatic inhibition of EA tumor formation. Tumor suppression required viable, infectious virus. Mice that had survived one EA-MVM coinjection acquired long-term resistance to additional injections of EA cells.

Original language	English
Pages (from-to)	1177-1180
Number of pages	4
Journal	Journal of the National Cancer Institute
Volume	76
Issue number	6
DOIs	https://doi.org/10.1093/jnci/76.6.1177
State	Published - 1 Jan 1986

ASJC Scopus subject areas

Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1093/jnci/76.6.1177

Cite this

@article{d2e3bd3fc6a64a09b358265102614419,

title = "Suppression of ehrlich ascites tumors in mice by minute virus of mice",

abstract = "As a model system to study parvoviral oncosuppression, Ehrlich ascites (EA) cells were injected into the peritoneal cavities of ICR mice, and the effect of im injection of minute virus of mice (MVM) on EA tumor growth was examined. Coinjection with MVM resulted in a dramatic inhibition of EA tumor formation. Tumor suppression required viable, infectious virus. Mice that had survived one EA-MVM coinjection acquired long-term resistance to additional injections of EA cells.",

author = "Esther Guetta and Yosef Graziani and Jacov Tal",

note = "Funding Information: 1 Received June 21, 1985; revised January 2, 1986; accepted January 13, 1986. 2 Supported by grants from the United States-Israel Binational Science Foundation and from the David Laser Memorial Fund of the Israel Cancer Research Fund. 3 Department of Biology, Ben-Gurion University of the Negev, BeerSheva 84105, Israel. 4We thank Dr. Jim Trempe for critical review of this manuscript.",

year = "1986",

month = jan,

day = "1",

doi = "10.1093/jnci/76.6.1177",

language = "English",

volume = "76",

pages = "1177--1180",

journal = "Journal of the National Cancer Institute",

issn = "0027-8874",

publisher = "Oxford University Press",

number = "6",

}

TY - JOUR

T1 - Suppression of ehrlich ascites tumors in mice by minute virus of mice

AU - Guetta, Esther

AU - Graziani, Yosef

AU - Tal, Jacov

N1 - Funding Information: 1 Received June 21, 1985; revised January 2, 1986; accepted January 13, 1986. 2 Supported by grants from the United States-Israel Binational Science Foundation and from the David Laser Memorial Fund of the Israel Cancer Research Fund. 3 Department of Biology, Ben-Gurion University of the Negev, BeerSheva 84105, Israel. 4We thank Dr. Jim Trempe for critical review of this manuscript.

PY - 1986/1/1

Y1 - 1986/1/1

N2 - As a model system to study parvoviral oncosuppression, Ehrlich ascites (EA) cells were injected into the peritoneal cavities of ICR mice, and the effect of im injection of minute virus of mice (MVM) on EA tumor growth was examined. Coinjection with MVM resulted in a dramatic inhibition of EA tumor formation. Tumor suppression required viable, infectious virus. Mice that had survived one EA-MVM coinjection acquired long-term resistance to additional injections of EA cells.

AB - As a model system to study parvoviral oncosuppression, Ehrlich ascites (EA) cells were injected into the peritoneal cavities of ICR mice, and the effect of im injection of minute virus of mice (MVM) on EA tumor growth was examined. Coinjection with MVM resulted in a dramatic inhibition of EA tumor formation. Tumor suppression required viable, infectious virus. Mice that had survived one EA-MVM coinjection acquired long-term resistance to additional injections of EA cells.

UR - http://www.scopus.com/inward/record.url?scp=0022579367&partnerID=8YFLogxK

U2 - 10.1093/jnci/76.6.1177

DO - 10.1093/jnci/76.6.1177

M3 - Article

C2 - 3458953

AN - SCOPUS:0022579367

SN - 0027-8874

VL - 76

SP - 1177

EP - 1180

JO - Journal of the National Cancer Institute

JF - Journal of the National Cancer Institute

IS - 6

ER -

Suppression of ehrlich ascites tumors in mice by minute virus of mice

Abstract

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this