Suppression of ehrlich ascites tumors in mice by minute virus of mice

Esther Guetta, Yosef Graziani, Jacov Tal

Research output: Contribution to journalArticlepeer-review

53 Scopus citations


As a model system to study parvoviral oncosuppression, Ehrlich ascites (EA) cells were injected into the peritoneal cavities of ICR mice, and the effect of im injection of minute virus of mice (MVM) on EA tumor growth was examined. Coinjection with MVM resulted in a dramatic inhibition of EA tumor formation. Tumor suppression required viable, infectious virus. Mice that had survived one EA-MVM coinjection acquired long-term resistance to additional injections of EA cells.

Original languageEnglish
Pages (from-to)1177-1180
Number of pages4
JournalJournal of the National Cancer Institute
Issue number6
StatePublished - 1 Jan 1986

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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