Suppressive effect of 1,2 dibromo 3 chloropropane on human spermatogenesis

G. Potashnik; N. Ben-Aderet; R. Israeli; I. Yanai-Inbar; I. Sober

doi:10.1016/S0015-0282(16)43580-6

Suppressive effect of 1,2 dibromo 3 chloropropane on human spermatogenesis

G. Potashnik, N. Ben-Aderet, R. Israeli, I. Yanai-Inbar, I. Sober

Research output: Contribution to journal › Article › peer-review

94 Scopus citations

Abstract

Azoospermia was diagnosed in six factory workers who had been chronically exposed to 1,2-dibromo-3-chloropropane. Infertility was the presenting symptom in two patients and a decrease in libido or impotence characterized the others. Hormone studies revealed elevated plasma follicle hormone levels and normal plasma luteinizing hormone and testosterone concentrations. Testicular biopsy showed selective atrophy of the germinal epithelium, intact Sertoli cells and a normal appearance of a relatively increased number of Leydig cells.

Original language	English
Pages (from-to)	444-447
Number of pages	4
Journal	Unknown Journal
Volume	30
Issue number	4
DOIs	https://doi.org/10.1016/S0015-0282(16)43580-6
State	Published - 1 Jan 1978

ASJC Scopus subject areas

Reproductive Medicine
Obstetrics and Gynecology

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abstract = "Azoospermia was diagnosed in six factory workers who had been chronically exposed to 1,2-dibromo-3-chloropropane. Infertility was the presenting symptom in two patients and a decrease in libido or impotence characterized the others. Hormone studies revealed elevated plasma follicle hormone levels and normal plasma luteinizing hormone and testosterone concentrations. Testicular biopsy showed selective atrophy of the germinal epithelium, intact Sertoli cells and a normal appearance of a relatively increased number of Leydig cells.",

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AU - Ben-Aderet, N.

AU - Israeli, R.

AU - Yanai-Inbar, I.

AU - Sober, I.

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AB - Azoospermia was diagnosed in six factory workers who had been chronically exposed to 1,2-dibromo-3-chloropropane. Infertility was the presenting symptom in two patients and a decrease in libido or impotence characterized the others. Hormone studies revealed elevated plasma follicle hormone levels and normal plasma luteinizing hormone and testosterone concentrations. Testicular biopsy showed selective atrophy of the germinal epithelium, intact Sertoli cells and a normal appearance of a relatively increased number of Leydig cells.

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Suppressive effect of 1,2 dibromo 3 chloropropane on human spermatogenesis

Abstract

ASJC Scopus subject areas

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