SURVEILLANCE OF CARBAPENEM-RESISTANT GRAM-NEGATIVE BACTERIA FROM ANIMAL SOURCES IN MATHURA REGION, UTTAR PRADESH, INDIA

A. Arun, U. Jaiswal, S. Tripathi, A. P. Singh, S. Choudhury, S. N. Prabhu

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

A cross-sectional study was conducted to determine the prevalence of Carbapenem-resistant Gram-negative bacteria (CR-GNB) in animals. The study involves one hundred eighty-four GNB isolates from 214 samples (faeces, milk, pus, and uterine discharge) from Buffalo (N=112), Cattle (N=50) and, Dog (N=52). Healthy and diseased animals reported to Veterinary Clinical Complex were sampled. Carbapenemase production was evaluated by phenotypic methods and presence of metallo b-lactamase genes was assayed by PCR. We observed a 9.78% overall prevalence of CR-GNB in animal sources. CR-GNB was more frequently recovered from companion animals (19.23%) when compared to livestock (4.93%). IMP (44.4%), VIM (38.8%), and OXA-48 (16.66 %) were the main MBLs observed in the study.

Original languageEnglish
Pages (from-to)91-98
Number of pages8
JournalExploratory Animal and Medical Research
Volume12
Issue number1
DOIs
StatePublished - 1 Jun 2022
Externally publishedYes

Keywords

  • Animals
  • Antibiotic resistance
  • Carbapenem
  • Gram-negative bacteria

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Ecology
  • General Veterinary
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

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