Swelling Behavior of Glucose Sensitive Membranes

Thomas A. Horbett, Joseph Kost, Buddy D. Ratner

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

27 Scopus citations


Polymers which are sensitive to their environment may be useful as metabolic sensors. Because of the great need for a glucose sensor which could be used in vivo to enhance treatment of diabetics, we are developing membranes responsive to glucose by incorporating glucose oxidase into amine-containing polymers. The conversion of glucose into gluconic acid in the membrane causes increased protonation of the membrane, resulting in increased membrane swelling. This paper describes the preparation and swelling properties of glucose sensitive membranes of this type.

Original languageEnglish
Title of host publicationPolymers as Biomaterials
EditorsShalaby W. Shalaby, Allan S. Hoffman, Buddy D. Ratner, Thomas A. Horbett
PublisherPlenum Press
Number of pages15
ISBN (Print)030641886X, 9780306418860
StatePublished - 1984
Externally publishedYes

ASJC Scopus subject areas

  • General Engineering


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