Swelling of glucose-responsive gels functionalized with boronic acid

A. D. Drozdov; J. de C. Christiansen

doi:10.1016/j.jmbbm.2016.09.021

Swelling of glucose-responsive gels functionalized with boronic acid

A. D. Drozdov, J. de C. Christiansen

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

A model is developed for the elastic response of a glucose-sensitive gel functionalized with boronic acid under swelling in aqueous solutions of glucose with various pH. A gel is treated as a three-phase medium composed of a solid phase (partially ionized polymer network), solvent (water), and solute (mobile glucose molecules and ions). Constitutive equations are derived by means of the free energy imbalance inequality for three-dimensional deformation with finite strains. Numerical analysis demonstrates the ability of the model to describe the effects of pH, molar fraction of glucose, and concentration of functional groups on equilibrium water uptake diagrams under unconstrained and constrained swelling.

Original language	English
Pages (from-to)	533-541
Number of pages	9
Journal	Journal of the Mechanical Behavior of Biomedical Materials
Volume	65
DOIs	https://doi.org/10.1016/j.jmbbm.2016.09.021
State	Published - 1 Jan 2017
Externally published	Yes

Keywords

Boronic acid
Glucose-responsive gel
Polyelectrolyte
Swelling

ASJC Scopus subject areas

Biomaterials
Biomedical Engineering
Mechanics of Materials

Access to Document

10.1016/j.jmbbm.2016.09.021

Cite this

@article{748a4102ff0d419e808b8753fb567751,

title = "Swelling of glucose-responsive gels functionalized with boronic acid",

abstract = "A model is developed for the elastic response of a glucose-sensitive gel functionalized with boronic acid under swelling in aqueous solutions of glucose with various pH. A gel is treated as a three-phase medium composed of a solid phase (partially ionized polymer network), solvent (water), and solute (mobile glucose molecules and ions). Constitutive equations are derived by means of the free energy imbalance inequality for three-dimensional deformation with finite strains. Numerical analysis demonstrates the ability of the model to describe the effects of pH, molar fraction of glucose, and concentration of functional groups on equilibrium water uptake diagrams under unconstrained and constrained swelling.",

keywords = "Boronic acid, Glucose-responsive gel, Polyelectrolyte, Swelling",

author = "Drozdov, {A. D.} and Christiansen, {J. de C.}",

note = "Publisher Copyright: {\textcopyright} 2016 Elsevier Ltd",

year = "2017",

month = jan,

day = "1",

doi = "10.1016/j.jmbbm.2016.09.021",

language = "English",

volume = "65",

pages = "533--541",

journal = "Journal of the Mechanical Behavior of Biomedical Materials",

issn = "1751-6161",

publisher = "Elsevier BV",

}

TY - JOUR

T1 - Swelling of glucose-responsive gels functionalized with boronic acid

AU - Drozdov, A. D.

AU - Christiansen, J. de C.

PY - 2017/1/1

Y1 - 2017/1/1

N2 - A model is developed for the elastic response of a glucose-sensitive gel functionalized with boronic acid under swelling in aqueous solutions of glucose with various pH. A gel is treated as a three-phase medium composed of a solid phase (partially ionized polymer network), solvent (water), and solute (mobile glucose molecules and ions). Constitutive equations are derived by means of the free energy imbalance inequality for three-dimensional deformation with finite strains. Numerical analysis demonstrates the ability of the model to describe the effects of pH, molar fraction of glucose, and concentration of functional groups on equilibrium water uptake diagrams under unconstrained and constrained swelling.

AB - A model is developed for the elastic response of a glucose-sensitive gel functionalized with boronic acid under swelling in aqueous solutions of glucose with various pH. A gel is treated as a three-phase medium composed of a solid phase (partially ionized polymer network), solvent (water), and solute (mobile glucose molecules and ions). Constitutive equations are derived by means of the free energy imbalance inequality for three-dimensional deformation with finite strains. Numerical analysis demonstrates the ability of the model to describe the effects of pH, molar fraction of glucose, and concentration of functional groups on equilibrium water uptake diagrams under unconstrained and constrained swelling.

KW - Boronic acid

KW - Glucose-responsive gel

KW - Polyelectrolyte

KW - Swelling

UR - http://www.scopus.com/inward/record.url?scp=84988981458&partnerID=8YFLogxK

U2 - 10.1016/j.jmbbm.2016.09.021

DO - 10.1016/j.jmbbm.2016.09.021

M3 - Article

C2 - 27697715

AN - SCOPUS:84988981458

SN - 1751-6161

VL - 65

SP - 533

EP - 541

JO - Journal of the Mechanical Behavior of Biomedical Materials

JF - Journal of the Mechanical Behavior of Biomedical Materials

ER -

Swelling of glucose-responsive gels functionalized with boronic acid

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this