Synergistic antileukemic activity of carnosic acid-rich rosemary extract and the 19-nor Gemini vitamin D analogue in a mouse model of systemic acute myeloid leukemia

Keyphrases

• Gemini 100%
• Acute Myeloid Leukemia 100%
• Carnosic Acid 100%
• Mouse Model 100%
• Vitamin D Analogs 100%
• Antileukemic Activity 100%
• Rosemary Extract 100%
• 1,25-dihydroxyvitamin D3 66%
• Combined Treatment 33%
• Rosemary 33%
• 1,25D 33%
• Cell Culture 16%
• Intravenous Injection 16%
• EC50 16%
• Therapeutic Approaches 16%
• Antiproliferative Activity 16%
• Flow Cytometry 16%
• IC50 16%
• Reactive Oxygen Species 16%
• Growth Arrest 16%
• Syngeneic 16%
• Leukemia 16%
• Antioxidant System 16%
• White Blood Cell Count 16%
• Methyl 16%
• Hypercalcemia 16%
• Vitamin D 16%
• Western Blotting 16%
• Enzymatic Assay 16%
• Differential Cell Count 16%
• Differentiation Therapy 16%
• Toxic Dose 16%
• Protein Expression Level 16%
• Pharmacologically Active 16%
• Glutathione 16%
• Differentiation Effect 16%
• Polyphenolics 16%
• Cholecalciferol 16%
• High Potency 16%
• Blood Differentials 16%
• Vitamin D Derivatives 16%
• Butyl 16%
• Parent Compounds 16%
• Human Leukemia 16%
• Rosemary Leaves 16%
• Myelomonocytic Leukemia 16%
• In Vitro Toxicity 16%
• Translational Model 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Acute Myeloid Leukemia 100%
• Mouse Model 100%
• Carnosic Acid 100%
• Vitamin D Analog 100%
• Rosmarinus Officinalis Extract 100%
• Mouse 80%
• Calcitriol 80%
• Rosemary 60%
• Leukemia 40%
• EC50 20%
• Flow Cytometry 20%
• Western Blot 20%
• IC50 20%
• Antioxidant 20%
• Cell Culture 20%
• Glutathione 20%
• Growth Disorder 20%
• Vitamin D 20%
• Reactive Oxygen Metabolite 20%
• Cholecalciferol 20%
• Hypercalcaemia 20%
• Vitamin D Derivative 20%
• Myelomonocytic Leukemia 20%

Medicine and Dentistry

• Acute Myeloid Leukemia 100%
• Carnosic Acid 100%
• Vitamin D Analog 100%
• Rosmarinus Officinalis Extract 100%
• Calcitriol 80%
• In Vitro 40%
• Leukemia 40%
• Protein Expression 20%
• Flow Cytometry 20%
• Intravenous Drug Administration 20%
• IC50 20%
• Growth Disorder 20%
• Western Blot 20%
• Antioxidant 20%
• Leukocyte 20%
• Vitamin D 20%
• Colecalciferol 20%
• Cell Culture 20%
• Reactive Oxygen Species 20%
• Hypercalcaemia 20%
• Glutathione 20%
• Differentiation Therapy 20%
• Vitamin D Derivative 20%
• Myelomonocytic Leukemia 20%
• Enzymatic Assay 20%