Abstract
The synthesis of some novel imidazole-based dicationic sulfonophanes incorporating various spacer units is described. All the sulphonophanes exhibit good antibacterial and antifungal activity against five bacterial strains Bacillus subtilis, Staphylococcus aureus, Vibrio cholera, Escherichia coli, Proteus vulgaris and human pathogenic fungus Candida albicans.
Original language | English |
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Pages (from-to) | 3093-3098 |
Number of pages | 6 |
Journal | European Journal of Medicinal Chemistry |
Volume | 46 |
Issue number | 7 |
DOIs | |
State | Published - 1 Jul 2011 |
Externally published | Yes |
Keywords
- Antibacterial activity
- Antifungal activity
- Dicationic sulphonophanes
- Imidazole
ASJC Scopus subject areas
- Pharmacology
- Drug Discovery
- Organic Chemistry