Synthesis and antimicrobial activity of some novel dicationic sulphonophanes

Perumal Rajakumar, Chinnadurai Satheeshkumar, Gunasekaran Mohanraj, Narayanasamy Mathivanan

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

The synthesis of some novel imidazole-based dicationic sulfonophanes incorporating various spacer units is described. All the sulphonophanes exhibit good antibacterial and antifungal activity against five bacterial strains Bacillus subtilis, Staphylococcus aureus, Vibrio cholera, Escherichia coli, Proteus vulgaris and human pathogenic fungus Candida albicans.

Original languageEnglish
Pages (from-to)3093-3098
Number of pages6
JournalEuropean Journal of Medicinal Chemistry
Volume46
Issue number7
DOIs
StatePublished - 1 Jul 2011
Externally publishedYes

Keywords

  • Antibacterial activity
  • Antifungal activity
  • Dicationic sulphonophanes
  • Imidazole

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery
  • Organic Chemistry

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