Synthesis and characterization of Au102(p -MBA)44 nanoparticles

Yael Levi-Kalisman, Pablo D. Jadzinsky, Nir Kalisman, Hironori Tsunoyama, Tatsuya Tsukuda, David A. Bushnell, Roger D. Kornberg

Research output: Contribution to journalArticlepeer-review

209 Scopus citations


The synthesis of Au102(p-MBA)44 nanoparticles on a preparative scale in high yield is described. Various analytical methods are shown to give results consistent with the composition and known structure of the particles, showing the preparation is essentially homogeneous, and attesting to the validity of the methods as well. Derivatization of the particles with proteins and DNA is demonstrated, and conditions are described for imaging individual particles by cryo-EM at low electron dose, close to focus, conditions optimal for recording high-resolution details.

Original languageEnglish
Pages (from-to)2976-2982
Number of pages7
JournalJournal of the American Chemical Society
Issue number9
StatePublished - 9 Mar 2011
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry
  • Biochemistry
  • Colloid and Surface Chemistry


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