Synthesis and characterization of PCU@C-Ag/AgCl nanoparticles as an antimicrobial material for respiratory tract infection

Senthilkumar Palanisamy; Kalaivani Subramanian; Lerince Godrina Bennet; Janani Ambrose; Aganiya Gopalakrishnan; Sudhagar Babu; Ranjithkumar Rajamani; Niraj Kumar Jha; Soumya Pandit; Sachin Kumar Singh; Kamal Dua; Piyush Kumar Gupta

doi:10.1515/nanofab-2020-0106

Synthesis and characterization of PCU@C-Ag/AgCl nanoparticles as an antimicrobial material for respiratory tract infection

Senthilkumar Palanisamy
, Kalaivani Subramanian
, Lerince Godrina Bennet
, Janani Ambrose
, Aganiya Gopalakrishnan
, Sudhagar Babu
, Ranjithkumar Rajamani
, Niraj Kumar Jha
, Soumya Pandit
, Sachin Kumar Singh
, Kamal Dua
, Piyush Kumar Gupta

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The pregnant cow urine (PCU) is an active source of antimicrobial agents that is used for fabricating chitosan coated Ag/AgCl nanoparticles (NPs) in the present study. These PCU@C-Ag/AgCl NPs were physicochemically characterized and evaluated for antimicrobial activity against selected respiratory tract infection (RTI) pathogens. The absorption band around 420 nm in UV-Visible spectrum indicated the presence of Ag NPs. The spherical shape of NPs was observed using TEM. Also, the crystalline structure was confirmed using the XRD pattern. The PCU@C-Ag/AgCl NPs showed strong antimicrobial activity against all tested RTI pathogens. In addition, FESEM analysis showed morphological changes in RTI bacterial pathogens. Thereby, PCU@C-Ag/AgCl NPs may be used as an antimicrobial material to treat RTIs in near future at clinical level.

Original language	English
Pages (from-to)	68-78
Number of pages	11
Journal	Nanofabrication
Volume	6
DOIs	https://doi.org/10.1515/nanofab-2020-0106
State	Published - 1 Jan 2021
Externally published	Yes

Keywords

Ag/AgCl nanoparticles
antimicrobial activity
chitosan
pregnant cow urine
respiratory tract infection pathogens

ASJC Scopus subject areas

Biotechnology
Bioengineering
Process Chemistry and Technology
Industrial and Manufacturing Engineering

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10.1515/nanofab-2020-0106

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@article{8ec26ccdc5d44167bfcce52443f670ed,

title = "Synthesis and characterization of PCU@C-Ag/AgCl nanoparticles as an antimicrobial material for respiratory tract infection",

abstract = "The pregnant cow urine (PCU) is an active source of antimicrobial agents that is used for fabricating chitosan coated Ag/AgCl nanoparticles (NPs) in the present study. These PCU@C-Ag/AgCl NPs were physicochemically characterized and evaluated for antimicrobial activity against selected respiratory tract infection (RTI) pathogens. The absorption band around 420 nm in UV-Visible spectrum indicated the presence of Ag NPs. The spherical shape of NPs was observed using TEM. Also, the crystalline structure was confirmed using the XRD pattern. The PCU@C-Ag/AgCl NPs showed strong antimicrobial activity against all tested RTI pathogens. In addition, FESEM analysis showed morphological changes in RTI bacterial pathogens. Thereby, PCU@C-Ag/AgCl NPs may be used as an antimicrobial material to treat RTIs in near future at clinical level.",

keywords = "Ag/AgCl nanoparticles, antimicrobial activity, chitosan, pregnant cow urine, respiratory tract infection pathogens",

author = "Senthilkumar Palanisamy and Kalaivani Subramanian and Bennet, \{Lerince Godrina\} and Janani Ambrose and Aganiya Gopalakrishnan and Sudhagar Babu and Ranjithkumar Rajamani and Jha, \{Niraj Kumar\} and Soumya Pandit and Singh, \{Sachin Kumar\} and Kamal Dua and Gupta, \{Piyush Kumar\}",

note = "Publisher Copyright: {\textcopyright} 2021 S. Palanisamy et al.",

year = "2021",

month = jan,

day = "1",

doi = "10.1515/nanofab-2020-0106",

language = "English",

volume = "6",

pages = "68--78",

journal = "Nanofabrication",

issn = "2299-680X",

publisher = "Eurasia Academic Publishing Group",

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TY - JOUR

T1 - Synthesis and characterization of PCU@C-Ag/AgCl nanoparticles as an antimicrobial material for respiratory tract infection

AU - Palanisamy, Senthilkumar

AU - Subramanian, Kalaivani

AU - Bennet, Lerince Godrina

AU - Ambrose, Janani

AU - Gopalakrishnan, Aganiya

AU - Babu, Sudhagar

AU - Rajamani, Ranjithkumar

AU - Jha, Niraj Kumar

AU - Pandit, Soumya

AU - Singh, Sachin Kumar

AU - Dua, Kamal

AU - Gupta, Piyush Kumar

PY - 2021/1/1

Y1 - 2021/1/1

N2 - The pregnant cow urine (PCU) is an active source of antimicrobial agents that is used for fabricating chitosan coated Ag/AgCl nanoparticles (NPs) in the present study. These PCU@C-Ag/AgCl NPs were physicochemically characterized and evaluated for antimicrobial activity against selected respiratory tract infection (RTI) pathogens. The absorption band around 420 nm in UV-Visible spectrum indicated the presence of Ag NPs. The spherical shape of NPs was observed using TEM. Also, the crystalline structure was confirmed using the XRD pattern. The PCU@C-Ag/AgCl NPs showed strong antimicrobial activity against all tested RTI pathogens. In addition, FESEM analysis showed morphological changes in RTI bacterial pathogens. Thereby, PCU@C-Ag/AgCl NPs may be used as an antimicrobial material to treat RTIs in near future at clinical level.

AB - The pregnant cow urine (PCU) is an active source of antimicrobial agents that is used for fabricating chitosan coated Ag/AgCl nanoparticles (NPs) in the present study. These PCU@C-Ag/AgCl NPs were physicochemically characterized and evaluated for antimicrobial activity against selected respiratory tract infection (RTI) pathogens. The absorption band around 420 nm in UV-Visible spectrum indicated the presence of Ag NPs. The spherical shape of NPs was observed using TEM. Also, the crystalline structure was confirmed using the XRD pattern. The PCU@C-Ag/AgCl NPs showed strong antimicrobial activity against all tested RTI pathogens. In addition, FESEM analysis showed morphological changes in RTI bacterial pathogens. Thereby, PCU@C-Ag/AgCl NPs may be used as an antimicrobial material to treat RTIs in near future at clinical level.

KW - Ag/AgCl nanoparticles

KW - antimicrobial activity

KW - chitosan

KW - pregnant cow urine

KW - respiratory tract infection pathogens

UR - https://www.scopus.com/pages/publications/105007015844

U2 - 10.1515/nanofab-2020-0106

DO - 10.1515/nanofab-2020-0106

M3 - Article

AN - SCOPUS:105007015844

SN - 2299-680X

VL - 6

SP - 68

EP - 78

JO - Nanofabrication

JF - Nanofabrication

ER -

Synthesis and characterization of PCU@C-Ag/AgCl nanoparticles as an antimicrobial material for respiratory tract infection

Abstract

Keywords

ASJC Scopus subject areas

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