Synthesis of α-silylcarboxylic acids

Alex V. Shtelman, James Y. Becker

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

New α-silylacetic acids have been prepared following a general and convenient procedure of a one-pot reaction between trimethylsilylacetate and different chlorosilanes. New derivatives of diphenyl(methyl)silylacetic acid were prepared by a direct alkylation of its dianion with benzyl-, allyl-, and alkyl halides and trimethylchlorogermane to afford new α-silylcarboxylic acids.

Original languageEnglish
Pages (from-to)1135-1141
Number of pages7
JournalTetrahedron
Volume67
Issue number6
DOIs
StatePublished - 11 Feb 2011

Keywords

  • Alkylation
  • Chlorosilanes
  • α, α′-Disilyldicarboxylic acids
  • α-Silylacetic acid dianion
  • α-Silylcarboxylic acids

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