Synthesis of 1,3,4-thiadiazole derivatives by the reaction of thiosemicarbazide or its 1- or 4-substituted derivatives with some 1-bromo-2-acylacetylenes

A. S. Nakhmanovich; T. E. Glotova; T. N. Komarova; M. V. Sigalov; L. S. Romanenko

doi:10.1007/BF00472199

Synthesis of 1,3,4-thiadiazole derivatives by the reaction of thiosemicarbazide or its 1- or 4-substituted derivatives with some 1-bromo-2-acylacetylenes

A. S. Nakhmanovich
, T. E. Glotova
, T. N. Komarova
, M. V. Sigalov
, L. S. Romanenko

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The reaction of thiosemicarbazide, 4-methyl-, 4-phenyl-, or 1-phenylthiosemicarbazides with 1-bromo-2-benzoyl(thenoyl-2)acetylenes in acetonitrile or glacial acetic acid yielded 2-acylmethylene- and 2-acylmethyl-5-amino-1,3,4-thiadiazoles. Heating of the latter in alcohol or aqueous alcohol gave the free bases.

Original language	English
Pages (from-to)	1186-1188
Number of pages	3
Journal	Chemistry of Heterocyclic Compounds
Volume	26
Issue number	10
DOIs	https://doi.org/10.1007/BF00472199
State	Published - 1 Oct 1990
Externally published	Yes

ASJC Scopus subject areas

Organic Chemistry

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title = "Synthesis of 1,3,4-thiadiazole derivatives by the reaction of thiosemicarbazide or its 1- or 4-substituted derivatives with some 1-bromo-2-acylacetylenes",

abstract = "The reaction of thiosemicarbazide, 4-methyl-, 4-phenyl-, or 1-phenylthiosemicarbazides with 1-bromo-2-benzoyl(thenoyl-2)acetylenes in acetonitrile or glacial acetic acid yielded 2-acylmethylene- and 2-acylmethyl-5-amino-1,3,4-thiadiazoles. Heating of the latter in alcohol or aqueous alcohol gave the free bases.",

author = "Nakhmanovich, \{A. S.\} and Glotova, \{T. E.\} and Komarova, \{T. N.\} and Sigalov, \{M. V.\} and Romanenko, \{L. S.\}",

year = "1990",

month = oct,

day = "1",

doi = "10.1007/BF00472199",

language = "English",

volume = "26",

pages = "1186--1188",

journal = "Chemistry of Heterocyclic Compounds",

issn = "0009-3122",

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TY - JOUR

T1 - Synthesis of 1,3,4-thiadiazole derivatives by the reaction of thiosemicarbazide or its 1- or 4-substituted derivatives with some 1-bromo-2-acylacetylenes

AU - Nakhmanovich, A. S.

AU - Glotova, T. E.

AU - Komarova, T. N.

AU - Sigalov, M. V.

AU - Romanenko, L. S.

PY - 1990/10/1

Y1 - 1990/10/1

N2 - The reaction of thiosemicarbazide, 4-methyl-, 4-phenyl-, or 1-phenylthiosemicarbazides with 1-bromo-2-benzoyl(thenoyl-2)acetylenes in acetonitrile or glacial acetic acid yielded 2-acylmethylene- and 2-acylmethyl-5-amino-1,3,4-thiadiazoles. Heating of the latter in alcohol or aqueous alcohol gave the free bases.

AB - The reaction of thiosemicarbazide, 4-methyl-, 4-phenyl-, or 1-phenylthiosemicarbazides with 1-bromo-2-benzoyl(thenoyl-2)acetylenes in acetonitrile or glacial acetic acid yielded 2-acylmethylene- and 2-acylmethyl-5-amino-1,3,4-thiadiazoles. Heating of the latter in alcohol or aqueous alcohol gave the free bases.

UR - https://www.scopus.com/pages/publications/34249962121

U2 - 10.1007/BF00472199

DO - 10.1007/BF00472199

M3 - Article

AN - SCOPUS:34249962121

SN - 0009-3122

VL - 26

SP - 1186

EP - 1188

JO - Chemistry of Heterocyclic Compounds

JF - Chemistry of Heterocyclic Compounds

IS - 10

ER -

Synthesis of 1,3,4-thiadiazole derivatives by the reaction of thiosemicarbazide or its 1- or 4-substituted derivatives with some 1-bromo-2-acylacetylenes

Abstract

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