Synthesis of 1,3,4-thiazole derivatives by the reaction of thiobenzhydrazide with some acylacetylenes

T. E. Glotova, A. S. Nakhmanovich, M. V. Sigalov

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

2-Acylmethyl-5-phenyl- and 3-acylvinyl-2-acylmethyl-5-phenyl-1,3,4-thiadiazol-4-ines were obtained by the reaction of terminal α-acetylenic ketones with thiobenzhydrazide. Substituted acetylenic ketones react with thiobenzhydrazide in alcohol to give N,S-bis(acylvinyl)thiobenzhydrazides.

Original languageEnglish
Pages (from-to)568-571
Number of pages4
JournalChemistry of Heterocyclic Compounds
Volume25
Issue number5
DOIs
StatePublished - 1 May 1989
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry

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