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Synthesis of 2-alkyl substituted benzimidazoles under microwave irradiation: Anti-proliferative effect of some representative compounds on human histiocytic lymphoma cell U937

  • Chhanda Mukhopadhyay
  • , Sabari Ghosh
  • , Sumita Sengupta
  • , Soumasree De

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

The objective of this research was the synthesis of 2-alkyl substituted benzimidazoles under microwave irradiation using 62% aqueous hexafluorophosphoric acid (10 mol%) as catalyst. Some of the newly synthesised compounds were tested for their potential to inhibit proliferation of cancer cells (histiocytic lymphoma cell U937) by cell viability assay.

Original languageEnglish
Pages (from-to)1033-1037
Number of pages5
JournalRSC Advances
Volume1
Issue number6
DOIs
StatePublished - 21 Oct 2011
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

ASJC Scopus subject areas

  • General Chemistry
  • General Chemical Engineering

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