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Synthesis of Fluorinated 2-Benzylphthalazin-1(2 H)-one, 1-Phthalazinamine, and 1-Alkoxy/Benzyloxyphthalazine Derivatives by an Ultrasonication Method

  • Mohanreddy Pothireddy
  • , Gurupada Hazra
  • , Penke Vijaya Babu
  • , Barla Thirupathi
  • , Rambabu Dandela

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Fluorinated heterocyclic compounds have been proven to exhibit interesting potential biological activities. Therefore, various fluorinated 2-benzylphthalazine-1(2H)-one and phthalazine-1-amine derivatives and nonfluorinated 1-alkoxy/benzyloxyphthalazines derivatives have been synthesized by an ultrasonication method. This protocol is more efficient than the conventional method in terms of its product yield and reaction handling and timelines.

Original languageEnglish
Pages (from-to)1716-1722
Number of pages7
JournalSynlett
Volume33
Issue number17
DOIs
StatePublished - 6 Oct 2022
Externally publishedYes

Keywords

  • benzylphthalazinones
  • fluorinated heterocycles
  • phthalazinamines
  • phthalazines
  • sonochemistry
  • ultrasound

ASJC Scopus subject areas

  • Organic Chemistry

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