Synthesis of functionalized naphthalenes by copper(I)-catalyzed annulation between 3-(2-Halobenzyl)pentane-2,4-diones and b-keto esters, malonates and cyanoacetates

Kavitha Sudheendran; Chandi C. Malakar; Jürgen Conrad; Uwe Beifuss

doi:10.1002/adsc.201300372

Synthesis of functionalized naphthalenes by copper(I)-catalyzed annulation between 3-(2-Halobenzyl)pentane-2,4-diones and b-keto esters, malonates and cyanoacetates

Kavitha Sudheendran, Chandi C. Malakar, Jürgen Conrad, Uwe Beifuss

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

The copper(I)-catalyzed domino reactions between the easily accessible 3-(2-halobenzyl)pentane-2,4-diones and β-keto esters, malonates and cyanoacetates afford trisubstituted naphthoates and naphthonitriles with yields up to 85%.

Original language	English
Pages (from-to)	2400-2416
Number of pages	17
Journal	Advanced Synthesis and Catalysis
Volume	355
Issue number	11-12
DOIs	https://doi.org/10.1002/adsc.201300372
State	Published - 12 Aug 2013
Externally published	Yes

Keywords

Annulation
C-C coupling
Catalysis
Domino reactions
Functionalized naphthalenes
Synthetic methods

ASJC Scopus subject areas

Catalysis
Organic Chemistry

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10.1002/adsc.201300372

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title = "Synthesis of functionalized naphthalenes by copper(I)-catalyzed annulation between 3-(2-Halobenzyl)pentane-2,4-diones and b-keto esters, malonates and cyanoacetates",

abstract = "The copper(I)-catalyzed domino reactions between the easily accessible 3-(2-halobenzyl)pentane-2,4-diones and β-keto esters, malonates and cyanoacetates afford trisubstituted naphthoates and naphthonitriles with yields up to 85%.",

keywords = "Annulation, C-C coupling, Catalysis, Domino reactions, Functionalized naphthalenes, Synthetic methods",

author = "Kavitha Sudheendran and Malakar, {Chandi C.} and J{\"u}rgen Conrad and Uwe Beifuss",

year = "2013",

month = aug,

day = "12",

doi = "10.1002/adsc.201300372",

language = "English",

volume = "355",

pages = "2400--2416",

journal = "Advanced Synthesis and Catalysis",

issn = "1615-4150",

publisher = "Wiley-VCH Verlag",

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Synthesis of functionalized naphthalenes by copper(I)-catalyzed annulation between 3-(2-Halobenzyl)pentane-2,4-diones and b-keto esters, malonates and cyanoacetates. / Sudheendran, Kavitha; Malakar, Chandi C.; Conrad, Jürgen et al.
In: Advanced Synthesis and Catalysis, Vol. 355, No. 11-12, 12.08.2013, p. 2400-2416.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Synthesis of functionalized naphthalenes by copper(I)-catalyzed annulation between 3-(2-Halobenzyl)pentane-2,4-diones and b-keto esters, malonates and cyanoacetates

AU - Sudheendran, Kavitha

AU - Malakar, Chandi C.

AU - Conrad, Jürgen

AU - Beifuss, Uwe

PY - 2013/8/12

Y1 - 2013/8/12

N2 - The copper(I)-catalyzed domino reactions between the easily accessible 3-(2-halobenzyl)pentane-2,4-diones and β-keto esters, malonates and cyanoacetates afford trisubstituted naphthoates and naphthonitriles with yields up to 85%.

AB - The copper(I)-catalyzed domino reactions between the easily accessible 3-(2-halobenzyl)pentane-2,4-diones and β-keto esters, malonates and cyanoacetates afford trisubstituted naphthoates and naphthonitriles with yields up to 85%.

KW - Annulation

KW - C-C coupling

KW - Catalysis

KW - Domino reactions

KW - Functionalized naphthalenes

KW - Synthetic methods

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DO - 10.1002/adsc.201300372

M3 - Article

AN - SCOPUS:84884501882

SN - 1615-4150

VL - 355

SP - 2400

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JO - Advanced Synthesis and Catalysis

JF - Advanced Synthesis and Catalysis

IS - 11-12

ER -

Synthesis of functionalized naphthalenes by copper(I)-catalyzed annulation between 3-(2-Halobenzyl)pentane-2,4-diones and b-keto esters, malonates and cyanoacetates

Abstract

Keywords

ASJC Scopus subject areas

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