Synthesis of Large Heterocyclic-Ring Fused Naphthoquinones

S Yerushalmi, S Bittner, Gabriel Lemcoff

Research output: Contribution to journalArticlepeer-review

Abstract

Reported is the straightforward four-step synthesis of four unsymmetrical naphthoquinone-fused 8- (diazacine), 9- (diazecine), and 10- (diazonine) membered ring heterocycles in good overall yields. The method takes advantage of double Michael addition-elimination as a prelude to an RCM process affording the indicated heterocycles in modest to good overall yields. Detailed NMR analysis and experimental procedures are provided.
Original languageEnglish GB
Pages (from-to)0469-0469
JournalSynfacts
Volume2007
Issue number05
DOIs
StatePublished - 2007

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