Synthesis of phosphorothioate-methylphosphonate oligonucleotide co-polymers

Liang Zhou; Alan M. Morocho; Ban chin Chen; Jack S. Cohen

doi:10.1093/nar/22.3.453

Synthesis of phosphorothioate-methylphosphonate oligonucleotide co-polymers

Liang Zhou, Alan M. Morocho, Ban chin Chen, Jack S. Cohen

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

We describe the synthesis and characterization of novel phosphorothloate-methylphosphonate backbone-modified ollgodeoxynucleotide co-polymers. These may have potential use as antlsense constructs.

Original language	English
Pages (from-to)	453-456
Number of pages	4
Journal	Nucleic Acids Research
Volume	22
Issue number	3
DOIs	https://doi.org/10.1093/nar/22.3.453
State	Published - 11 Feb 1994
Externally published	Yes

ASJC Scopus subject areas

Genetics

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title = "Synthesis of phosphorothioate-methylphosphonate oligonucleotide co-polymers",

abstract = "We describe the synthesis and characterization of novel phosphorothloate-methylphosphonate backbone-modified ollgodeoxynucleotide co-polymers. These may have potential use as antlsense constructs.",

author = "Liang Zhou and Morocho, {Alan M.} and Chen, {Ban chin} and Cohen, {Jack S.}",

year = "1994",

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doi = "10.1093/nar/22.3.453",

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journal = "Nucleic Acids Research",

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AU - Zhou, Liang

AU - Morocho, Alan M.

AU - Chen, Ban chin

AU - Cohen, Jack S.

PY - 1994/2/11

Y1 - 1994/2/11

N2 - We describe the synthesis and characterization of novel phosphorothloate-methylphosphonate backbone-modified ollgodeoxynucleotide co-polymers. These may have potential use as antlsense constructs.

AB - We describe the synthesis and characterization of novel phosphorothloate-methylphosphonate backbone-modified ollgodeoxynucleotide co-polymers. These may have potential use as antlsense constructs.

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M3 - Article

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AN - SCOPUS:0342436060

SN - 0305-1048

VL - 22

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EP - 456

JO - Nucleic Acids Research

JF - Nucleic Acids Research

IS - 3

ER -

Synthesis of phosphorothioate-methylphosphonate oligonucleotide co-polymers

Abstract

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