Abstract
Addition of polyfunctionalized aryl, heteroaryl, and tertiary alkylmagnesium reagents to tertiary nitroalkanes at 25A"°C in tetrahydrofuran produces, after reductive workup with FeCl2 and NaBH4 in ethanol, the corresponding polyfunctional secondary amines in high yields.
Original language | English |
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Article number | ss-2015-t0367-op |
Pages (from-to) | 3246-3256 |
Number of pages | 11 |
Journal | Synthesis (Germany) |
Volume | 47 |
Issue number | 20 |
DOIs | |
State | Published - 16 Oct 2015 |
Externally published | Yes |
Keywords
- adamantane
- amination reactions
- nitroalkanes
- organomagnesium reagents
- secondary amines
ASJC Scopus subject areas
- Catalysis
- Organic Chemistry