Synthetic method to access fluorinated 2-benzylpyridines by using Negishi coupling reaction

Mohanreddy Pothireddy; Swadhapriya Bhukta; P. Vijaya Babu; Barla Thirupathi; Rambabu Dandela

doi:10.1080/00397911.2022.2037651

Synthetic method to access fluorinated 2-benzylpyridines by using Negishi coupling reaction

Mohanreddy Pothireddy, Swadhapriya Bhukta, P. Vijaya Babu, Barla Thirupathi, Rambabu Dandela

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

2-Benzylpyridines scaffolds have been found in various drugs, bioactive natural products, and medicinally important compounds. This manuscript comprises the synthesis of various fluorinated analogs of 2-benzylpyridine compounds by using a Negishi coupling reaction as a key reaction.

Original language	English
Pages (from-to)	564-576
Number of pages	13
Journal	Synthetic Communications
Volume	52
Issue number	4
DOIs	https://doi.org/10.1080/00397911.2022.2037651
State	Published - 1 Jan 2022
Externally published	Yes

Keywords

2-Benzylpyridines
fluorinated compounds
medicinal chemistry
Negishi coupling

ASJC Scopus subject areas

Organic Chemistry

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10.1080/00397911.2022.2037651

Cite this

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abstract = "2-Benzylpyridines scaffolds have been found in various drugs, bioactive natural products, and medicinally important compounds. This manuscript comprises the synthesis of various fluorinated analogs of 2-benzylpyridine compounds by using a Negishi coupling reaction as a key reaction.",

keywords = "2-Benzylpyridines, fluorinated compounds, medicinal chemistry, Negishi coupling",

author = "Mohanreddy Pothireddy and Swadhapriya Bhukta and Babu, {P. Vijaya} and Barla Thirupathi and Rambabu Dandela",

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AU - Pothireddy, Mohanreddy

AU - Bhukta, Swadhapriya

AU - Babu, P. Vijaya

AU - Thirupathi, Barla

AU - Dandela, Rambabu

PY - 2022/1/1

Y1 - 2022/1/1

N2 - 2-Benzylpyridines scaffolds have been found in various drugs, bioactive natural products, and medicinally important compounds. This manuscript comprises the synthesis of various fluorinated analogs of 2-benzylpyridine compounds by using a Negishi coupling reaction as a key reaction.

AB - 2-Benzylpyridines scaffolds have been found in various drugs, bioactive natural products, and medicinally important compounds. This manuscript comprises the synthesis of various fluorinated analogs of 2-benzylpyridine compounds by using a Negishi coupling reaction as a key reaction.

KW - 2-Benzylpyridines

KW - fluorinated compounds

KW - medicinal chemistry

KW - Negishi coupling

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DO - 10.1080/00397911.2022.2037651

M3 - Article

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SN - 0039-7911

VL - 52

SP - 564

EP - 576

JO - Synthetic Communications

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ER -

Synthetic method to access fluorinated 2-benzylpyridines by using Negishi coupling reaction

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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