Taking angiotensin-converting enzyme inhibitors during pregnancy: Is it safe?

Almundher Al-Maawali, Asnat Walfisch, Gideon Koren

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations

    Abstract

    Question One of my 35-year-old pregnant patients has been treated with enalapril for primary hypertension. She learned she was pregnant at 11 weeks' gestation. I read somewhere that angiotensin-converting enzyme (ACE) inhibitors can cause malformations. What advice do you give to Motherisk callers? Answer Most published studies have failed to show an effect of ACE inhibitors on congenital malformations. A recent systematic review and meta-analysis conducted by Motherisk does not suggest increased fetal risk of malformations. However, ACE inhibitors should be avoided in late pregnancy, as they might cause renal failure and acalvaria in the baby.

    Original languageEnglish
    Pages (from-to)49-51
    Number of pages3
    JournalCanadian Family Physician
    Volume58
    Issue number1
    StatePublished - 1 Jan 2012

    ASJC Scopus subject areas

    • Family Practice

    Fingerprint

    Dive into the research topics of 'Taking angiotensin-converting enzyme inhibitors during pregnancy: Is it safe?'. Together they form a unique fingerprint.

    Cite this