Targeting prolonged short-term central venous catheters to reduce hospital-wide catheter days and CLABSI rates

Regev Cohen; Shelly Lipman-Arens; Lamis Mahamid; Linor Ishay; Olga Feld Simon; Sharon Reisfeld; Orna Ben-Natan; Aliza Vaknin; Mohammed Ganayem; Razi Abu Hadba; Erez Karisi; Noa Melnik; Sarit Freimann; Maanit Shapira; Nina Avshovich; Ayed Darawshe; Ronit Rachmilevitch; Valery Istomin; Rena Abilevitch; Saif Abu-Mouch; Rotem Novoselsky; Marinella Beckerman; Vlada Dubinchik; Boris Kessel; Veacheslav Zilbermints; Veronika Starobinsky; Inna Furman; Konstantin Neimark; Yaakov Daskal; Mohanad Ganayem; Fanny Biton; Boris Isakovich; Elias Tannous

doi:10.1016/j.ajic.2024.10.011

Targeting prolonged short-term central venous catheters to reduce hospital-wide catheter days and CLABSI rates

Regev Cohen, Shelly Lipman-Arens, Lamis Mahamid, Linor Ishay, Olga Feld Simon, Sharon Reisfeld, Orna Ben-Natan, Aliza Vaknin, Mohammed Ganayem, Razi Abu Hadba, Erez Karisi, Noa Melnik, Sarit Freimann, Maanit Shapira, Nina Avshovich, Ayed Darawshe, Ronit Rachmilevitch, Valery Istomin, Rena Abilevitch, Saif Abu-MouchRotem Novoselsky, Marinella Beckerman, Vlada Dubinchik, Boris Kessel, Veacheslav Zilbermints, Veronika Starobinsky, Inna Furman, Konstantin Neimark, Yaakov Daskal, Mohanad Ganayem, Fanny Biton, Boris Isakovich, Elias Tannous

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

Abstract

Background: The risk of central line-associated bloodstream infection (CLABSI) is associated with central venous catheter (CVC) dwelling time. We implemented a hospital-wide intervention aimed to alert physicians to CVC duration and necessity and to improve the monitoring of CLABSI prevention process measures outside the intensive care unit (ICU). Methods: A retrospective, before-after study that evaluated short-term, nonhemodialysis CVCs in and out of the ICU. The intervention included enhanced bundle-prevention measures monitoring and staff “sensitization” regarding prolonged (> 7 days) CVCs (pCVCs). The ICU intervention also included daily CVC-stewardship visits. We assessed CVC utilizations and CLABSI episodes 20 months before to 19 months after the intervention using Mann-Whitney tests. Results: Out of the ICU, CVC-utilization ratio (CVC-UR) and pCVC-UR reduced significantly (4.1-2.7/100 hospital days, P = .005; and 28%-21%, P = .02, respectively). Bundle-prevention measures improved, and CLABSI rates reduced postintervention (7.9-3.6/1,000 CVC days, P = .03). In the ICU, pCVC-UR reduced significantly (29%-15%, P < .0001). Baseline ICU-CLABSI rates were low and did not reduce postintervention. Conclusions: Sensitizing physicians to the existence and duration of CVCs accompanied by improved bundle-prevention measures, resulted in reduction of pCVCs, and outside the ICU, also in reduction of CVC-UR and CLABSI rates.

Original language	English
Pages (from-to)	361-367
Number of pages	7
Journal	American Journal of Infection Control
Volume	53
Issue number	3
DOIs	https://doi.org/10.1016/j.ajic.2024.10.011
State	Published - 1 Mar 2025

Keywords

Bundle
Catheter duration
Catheter related bloodstream infection
Idle catheter
Utilization ratio

ASJC Scopus subject areas

Epidemiology
Health Policy
Public Health, Environmental and Occupational Health
Infectious Diseases

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10.1016/j.ajic.2024.10.011

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Cohen, R., Lipman-Arens, S., Mahamid, L., Ishay, L., Feld Simon, O., Reisfeld, S., Ben-Natan, O., Vaknin, A., Ganayem, M., Abu Hadba, R., Karisi, E., Melnik, N., Freimann, S., Shapira, M., Avshovich, N., Darawshe, A., Rachmilevitch, R., Istomin, V., Abilevitch, R., ... Tannous, E. (2025). Targeting prolonged short-term central venous catheters to reduce hospital-wide catheter days and CLABSI rates. American Journal of Infection Control, 53(3), 361-367. https://doi.org/10.1016/j.ajic.2024.10.011

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title = "Targeting prolonged short-term central venous catheters to reduce hospital-wide catheter days and CLABSI rates",

abstract = "Background: The risk of central line-associated bloodstream infection (CLABSI) is associated with central venous catheter (CVC) dwelling time. We implemented a hospital-wide intervention aimed to alert physicians to CVC duration and necessity and to improve the monitoring of CLABSI prevention process measures outside the intensive care unit (ICU). Methods: A retrospective, before-after study that evaluated short-term, nonhemodialysis CVCs in and out of the ICU. The intervention included enhanced bundle-prevention measures monitoring and staff “sensitization” regarding prolonged (> 7 days) CVCs (pCVCs). The ICU intervention also included daily CVC-stewardship visits. We assessed CVC utilizations and CLABSI episodes 20 months before to 19 months after the intervention using Mann-Whitney tests. Results: Out of the ICU, CVC-utilization ratio (CVC-UR) and pCVC-UR reduced significantly (4.1-2.7/100 hospital days, P = .005; and 28\%-21\%, P = .02, respectively). Bundle-prevention measures improved, and CLABSI rates reduced postintervention (7.9-3.6/1,000 CVC days, P = .03). In the ICU, pCVC-UR reduced significantly (29\%-15\%, P < .0001). Baseline ICU-CLABSI rates were low and did not reduce postintervention. Conclusions: Sensitizing physicians to the existence and duration of CVCs accompanied by improved bundle-prevention measures, resulted in reduction of pCVCs, and outside the ICU, also in reduction of CVC-UR and CLABSI rates.",

keywords = "Bundle, Catheter duration, Catheter related bloodstream infection, Idle catheter, Utilization ratio",

author = "Regev Cohen and Shelly Lipman-Arens and Lamis Mahamid and Linor Ishay and \{Feld Simon\}, Olga and Sharon Reisfeld and Orna Ben-Natan and Aliza Vaknin and Mohammed Ganayem and \{Abu Hadba\}, Razi and Erez Karisi and Noa Melnik and Sarit Freimann and Maanit Shapira and Nina Avshovich and Ayed Darawshe and Ronit Rachmilevitch and Valery Istomin and Rena Abilevitch and Saif Abu-Mouch and Rotem Novoselsky and Marinella Beckerman and Vlada Dubinchik and Boris Kessel and Veacheslav Zilbermints and Veronika Starobinsky and Inna Furman and Konstantin Neimark and Yaakov Daskal and Mohanad Ganayem and Fanny Biton and Boris Isakovich and Elias Tannous",

note = "Publisher Copyright: {\textcopyright} 2024 Association for Professionals in Infection Control and Epidemiology, Inc.",

year = "2025",

month = mar,

day = "1",

doi = "10.1016/j.ajic.2024.10.011",

language = "English",

volume = "53",

pages = "361--367",

journal = "American Journal of Infection Control",

issn = "0196-6553",

publisher = "Elsevier Inc.",

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Cohen, R, Lipman-Arens, S, Mahamid, L, Ishay, L, Feld Simon, O, Reisfeld, S, Ben-Natan, O, Vaknin, A, Ganayem, M, Abu Hadba, R, Karisi, E, Melnik, N, Freimann, S, Shapira, M, Avshovich, N, Darawshe, A, Rachmilevitch, R, Istomin, V, Abilevitch, R, Abu-Mouch, S, Novoselsky, R, Beckerman, M, Dubinchik, V, Kessel, B, Zilbermints, V, Starobinsky, V, Furman, I, Neimark, K, Daskal, Y, Ganayem, M, Biton, F, Isakovich, B & Tannous, E 2025, 'Targeting prolonged short-term central venous catheters to reduce hospital-wide catheter days and CLABSI rates', American Journal of Infection Control, vol. 53, no. 3, pp. 361-367. https://doi.org/10.1016/j.ajic.2024.10.011

TY - JOUR

T1 - Targeting prolonged short-term central venous catheters to reduce hospital-wide catheter days and CLABSI rates

AU - Cohen, Regev

AU - Lipman-Arens, Shelly

AU - Mahamid, Lamis

AU - Ishay, Linor

AU - Feld Simon, Olga

AU - Reisfeld, Sharon

AU - Ben-Natan, Orna

AU - Vaknin, Aliza

AU - Ganayem, Mohammed

AU - Abu Hadba, Razi

AU - Karisi, Erez

AU - Melnik, Noa

AU - Freimann, Sarit

AU - Shapira, Maanit

AU - Avshovich, Nina

AU - Darawshe, Ayed

AU - Rachmilevitch, Ronit

AU - Istomin, Valery

AU - Abilevitch, Rena

AU - Abu-Mouch, Saif

AU - Novoselsky, Rotem

AU - Beckerman, Marinella

AU - Dubinchik, Vlada

AU - Kessel, Boris

AU - Zilbermints, Veacheslav

AU - Starobinsky, Veronika

AU - Furman, Inna

AU - Neimark, Konstantin

AU - Daskal, Yaakov

AU - Ganayem, Mohanad

AU - Biton, Fanny

AU - Isakovich, Boris

AU - Tannous, Elias

PY - 2025/3/1

Y1 - 2025/3/1

N2 - Background: The risk of central line-associated bloodstream infection (CLABSI) is associated with central venous catheter (CVC) dwelling time. We implemented a hospital-wide intervention aimed to alert physicians to CVC duration and necessity and to improve the monitoring of CLABSI prevention process measures outside the intensive care unit (ICU). Methods: A retrospective, before-after study that evaluated short-term, nonhemodialysis CVCs in and out of the ICU. The intervention included enhanced bundle-prevention measures monitoring and staff “sensitization” regarding prolonged (> 7 days) CVCs (pCVCs). The ICU intervention also included daily CVC-stewardship visits. We assessed CVC utilizations and CLABSI episodes 20 months before to 19 months after the intervention using Mann-Whitney tests. Results: Out of the ICU, CVC-utilization ratio (CVC-UR) and pCVC-UR reduced significantly (4.1-2.7/100 hospital days, P = .005; and 28%-21%, P = .02, respectively). Bundle-prevention measures improved, and CLABSI rates reduced postintervention (7.9-3.6/1,000 CVC days, P = .03). In the ICU, pCVC-UR reduced significantly (29%-15%, P < .0001). Baseline ICU-CLABSI rates were low and did not reduce postintervention. Conclusions: Sensitizing physicians to the existence and duration of CVCs accompanied by improved bundle-prevention measures, resulted in reduction of pCVCs, and outside the ICU, also in reduction of CVC-UR and CLABSI rates.

AB - Background: The risk of central line-associated bloodstream infection (CLABSI) is associated with central venous catheter (CVC) dwelling time. We implemented a hospital-wide intervention aimed to alert physicians to CVC duration and necessity and to improve the monitoring of CLABSI prevention process measures outside the intensive care unit (ICU). Methods: A retrospective, before-after study that evaluated short-term, nonhemodialysis CVCs in and out of the ICU. The intervention included enhanced bundle-prevention measures monitoring and staff “sensitization” regarding prolonged (> 7 days) CVCs (pCVCs). The ICU intervention also included daily CVC-stewardship visits. We assessed CVC utilizations and CLABSI episodes 20 months before to 19 months after the intervention using Mann-Whitney tests. Results: Out of the ICU, CVC-utilization ratio (CVC-UR) and pCVC-UR reduced significantly (4.1-2.7/100 hospital days, P = .005; and 28%-21%, P = .02, respectively). Bundle-prevention measures improved, and CLABSI rates reduced postintervention (7.9-3.6/1,000 CVC days, P = .03). In the ICU, pCVC-UR reduced significantly (29%-15%, P < .0001). Baseline ICU-CLABSI rates were low and did not reduce postintervention. Conclusions: Sensitizing physicians to the existence and duration of CVCs accompanied by improved bundle-prevention measures, resulted in reduction of pCVCs, and outside the ICU, also in reduction of CVC-UR and CLABSI rates.

KW - Bundle

KW - Catheter duration

KW - Catheter related bloodstream infection

KW - Idle catheter

KW - Utilization ratio

UR - http://www.scopus.com/inward/record.url?scp=85208411953&partnerID=8YFLogxK

U2 - 10.1016/j.ajic.2024.10.011

DO - 10.1016/j.ajic.2024.10.011

M3 - Article

C2 - 39427926

AN - SCOPUS:85208411953

SN - 0196-6553

VL - 53

SP - 361

EP - 367

JO - American Journal of Infection Control

JF - American Journal of Infection Control

IS - 3

ER -

Targeting prolonged short-term central venous catheters to reduce hospital-wide catheter days and CLABSI rates

Abstract

Keywords

ASJC Scopus subject areas

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