Teething and acute Graft Vs. Host Disease: A clinical observation

Joseph Shapira, Mamet Aker, Arnon Nagler, Reuven Or, Joseph Kapelushnik

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


A 5-month-old girl, treated with bone marrow transplantation for severe combined immunodeficiency, developed two episodes of severe acute graft Vs host disease (GVHD) while teething. A dramatic improvement in GVHD was noted after the completion of tooth eruption. It is suggested that the release of interleukin-1, associated with the traumatized gingival tissue, is the triggering mediator for the GVHD.

Original languageEnglish
Pages (from-to)159-160
Number of pages2
JournalJournal of Clinical Pediatric Dentistry
Issue number2
StatePublished - 1 Dec 1996
Externally publishedYes

ASJC Scopus subject areas

  • Medicine (all)


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