Temporal and seasonal trends in acanthamoeba keratitis

Penny McAllum, Irit Bahar, Igor Kaiserman, Sathish Srinivasan, Allan Slomovic, David Rootman

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


PURPOSE: The purpose of this study was to assess the incidence and risk factors of Acanthamoeba keratitis (AK) over an 8-year period in a Canadian tertiary care setting. METHODS: We retrospectively reviewed the medical records of 41 patients (42 eyes), who were diagnosed as having AK between January 1999 and December 2006 in the cornea clinic at the Toronto Western Hospital. The incidence and risk factors of AK were evaluated. RESULTS: The number of cases per year increased from between 0 and 4 in the first 5 years to 9, 14, and 8 in the last 3 years. The annual increasing trend was statistically significant (P = 0.04). The month of onset of disease symptoms showed a trend toward onset in summer and fall and was statistically significant for the difference between January and August (P = 0.0094). The season of onset of disease symptoms showed a trend toward summer onset, and the difference between winter and summer was statistically significant (P = 0.02). 92.9% of cases occurred in contact lens wearers, particularly in soft contact lens wearers (82.1%). CONCLUSIONS: The incidence of AK in Canada may be increasing since 2004. There is a seasonal trend toward disease onset in the warmer months.

Original languageEnglish
Pages (from-to)7-10
Number of pages4
Issue number1
StatePublished - 1 Jan 2009
Externally publishedYes


  • Acanthamoeba keratitis
  • Incidence
  • Risk factors

ASJC Scopus subject areas

  • Ophthalmology


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