The barriers to neonatal Hepatitis B vaccination in Israel: A prospective study

Elena Fridman, Liran Peretz-Aizenman, Abed N. Azab

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Background: Opposition to neonatal Hepatitis B vaccination is a growing trend in Israel. Objectives: To assess the sociodemographic factors and attitudes associated with non-vaccination of term singleton newborns. Methods: This prospective, pair-matched, controlled trial was conducted in a tertiary university-affiliated hospital. Data on maternal sociodemographic parameters, delivery, and infant care practices were gathered. Knowledge and references of Hepatitis B virus (HBV) vaccination, vaccination schedule, and health government policies were assessed. A followup telephone survey was completed at the age of 7 weeks postpartum regarding vaccine catch-up rate. Results: Mothers in the study group were mostly Jewish white middle class married multiparous women with some higher education. Hepatitis B serology was not tested in most. Higher rates of rooming-in and exclusive breastfeeding were observed. Knowledge about HBV was stated, multiple sources of information were significantly associated with newborn non-vaccination. Many objected to the timing of the vaccine and its necessity. Multiple medical encounters are viewed as missed opportunities. Conclusions: Multiple sources of vaccine information are associated with non-vaccination. Medical encounters prior and post-delivery should be used for vaccination education and may improve vaccination coverage.

Original languageEnglish
Pages (from-to)148-153
Number of pages6
JournalIsrael Medical Association Journal
Issue number3
StatePublished - 1 Mar 2020


  • Hepatitis B
  • Newborn
  • Non-vaccination
  • Prenatal education
  • Vaccination catch up


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