The burst of mitochondrial diseases: Neurons and calcium

Anna Fendyur; Igor Kaiserman; Lior Kasinetz; Rami Rahamimoff

The burst of mitochondrial diseases: Neurons and calcium

Anna Fendyur, Igor Kaiserman, Lior Kasinetz, Rami Rahamimoff

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

In summary, it seems that in many neurologic disorders - of both genetic and toxic origin - mitochondrial disruption leads to an altered calcium metabolism and thus to cell death. This raises the possibility that various protective agents, such as antioxidants, that improve mitochondrial function efficiency, may be of benefit in high risk individuals.

Original language	English
Pages (from-to)	356-359
Number of pages	4
Journal	Israel Medical Association Journal
Volume	6
Issue number	6
State	Published - 1 Jun 2004
Externally published	Yes

Keywords

Calcium
Genetic disease
Mitochondria
Neurotoxicity
Oxidative stress

ASJC Scopus subject areas

General Medicine

Cite this

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title = "The burst of mitochondrial diseases: Neurons and calcium",

abstract = "In summary, it seems that in many neurologic disorders - of both genetic and toxic origin - mitochondrial disruption leads to an altered calcium metabolism and thus to cell death. This raises the possibility that various protective agents, such as antioxidants, that improve mitochondrial function efficiency, may be of benefit in high risk individuals.",

keywords = "Calcium, Genetic disease, Mitochondria, Neurotoxicity, Oxidative stress",

author = "Anna Fendyur and Igor Kaiserman and Lior Kasinetz and Rami Rahamimoff",

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TY - JOUR

T1 - The burst of mitochondrial diseases

T2 - Neurons and calcium

AU - Fendyur, Anna

AU - Kaiserman, Igor

AU - Kasinetz, Lior

AU - Rahamimoff, Rami

PY - 2004/6/1

Y1 - 2004/6/1

N2 - In summary, it seems that in many neurologic disorders - of both genetic and toxic origin - mitochondrial disruption leads to an altered calcium metabolism and thus to cell death. This raises the possibility that various protective agents, such as antioxidants, that improve mitochondrial function efficiency, may be of benefit in high risk individuals.

AB - In summary, it seems that in many neurologic disorders - of both genetic and toxic origin - mitochondrial disruption leads to an altered calcium metabolism and thus to cell death. This raises the possibility that various protective agents, such as antioxidants, that improve mitochondrial function efficiency, may be of benefit in high risk individuals.

KW - Calcium

KW - Genetic disease

KW - Mitochondria

KW - Neurotoxicity

KW - Oxidative stress

UR - http://www.scopus.com/inward/record.url?scp=3042581958&partnerID=8YFLogxK

M3 - Review article

AN - SCOPUS:3042581958

SN - 1565-1088

VL - 6

SP - 356

EP - 359

JO - Israel Medical Association Journal

JF - Israel Medical Association Journal

IS - 6

ER -

The burst of mitochondrial diseases: Neurons and calcium

Abstract

Keywords

ASJC Scopus subject areas

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