Abstract
N. Zilberberg, E. Zlotkin and M. Gurevitz. The cDNA sequence of a depressant insect selective neurotoxin from the scorpion Buthotus judaicus. Toxicon 29, 1155-1158, 1991.-A 400 nucleotide cDNA clone encoding the depressant insect toxin of the scorpion Buthotus judaicus (BjIT2), was isolated. DNA sequence analysis suggests that the toxin is a processed product of a precursor composed of: (1) a 21 amino acid residue signal peptide; (2) a 61 amino acid region of the mature toxin; and (3) an additional Arg-Lys-Lys tail at the carboxy terminus prior to a termination codon. Comparison between the precursor polypeptides of BjIT2 and another depressant insect toxin derived from the scorpion Leiurus quinquestriatus hebraeus (LqhIT2) shows similarities in their hydropathic profiles.
Original language | English |
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Pages (from-to) | 1155-1158 |
Number of pages | 4 |
Journal | Toxicon |
Volume | 29 |
Issue number | 9 |
DOIs | |
State | Published - 1 Jan 1991 |
Externally published | Yes |
ASJC Scopus subject areas
- Toxicology