The dimethyltryptamine forming enzyme in blood platelets: a study in monozygotic twins discordant for schizophrenia

R. J. Wyatt, J. M. Saavedra, R. Belmaker, S. Cohen, W. Pollin

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Samples of the nondialyzed platelets of 14 pairs of monozygotic twins discordant for schizophrenia were assayed for their ability to enzymatically form the hallucinogen dimethyltryptamine. The schizophrenic twins had higher mean levels of enzyme activity than their non schizophrenic co twins, whose mean level of enzyme activity was equal to that of 22 normal subjects. This finding suggests that the higher level of enzyme activity found in schizophrenics is produced by their environment and is not genetically determined.

Original languageEnglish
Pages (from-to)1359-1361
Number of pages3
JournalAmerican Journal of Psychiatry
Volume130
Issue number12
DOIs
StatePublished - 1 Jan 1973
Externally publishedYes

ASJC Scopus subject areas

  • Psychiatry and Mental health

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