The dual association between lymphoma and autoimmunity

M. Ehrenfeld, M. Abu-Shakra, D. Buskila, Y. Shoenfeld

    Research output: Contribution to journalArticlepeer-review

    91 Scopus citations


    Autoimmune rheumatic diseases and lymphocytic malignancies are related and this association is bidirectional. Lymphomas occur more frequently in the course of autoimmune disease and autoimmune rheumatic manifestations occur in the course of lymphocytic malignancies. An increased incidence of malignant lymphocytic diseases is present in patients with rheumatoid arthritis, systemic lupus erythematosus, Sjögren’s syndrome, and autoimmune thyroid disease. Descriptions of lymphocytic malignancies among other autoimmune rheumatic disease have been published. In some patients, the malignant disease is diagnosed months or years before the appearance of the rheumatic disease.

    Original languageEnglish
    Pages (from-to)750-756
    Number of pages7
    JournalBlood Cells, Molecules, and Diseases
    Issue number4
    StatePublished - 1 Jan 2001


    • Lymphoma
    • Rheumatoid arthritis
    • SLE
    • Sjögren’s syndrome

    ASJC Scopus subject areas

    • Molecular Medicine
    • Molecular Biology
    • Hematology
    • Cell Biology


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