The effects of D aldosterone and spironolactone on the sodium and potassium concentrations in the milk of rats were determined. D Aldosterone caused a highly significant fall in the milk sodium concentration and the Na:K ratio when compared with control animals. The administration of spironolactone shortly before aldosterone gave results not significantly different from control animals. It is concluded that aldosterone has a specific sodium lowering action in the milk of the lactating rat.
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism