The effect of high pressure on the rate of decomposition of H2O2 by liver catalase

Yu M. Azizov; B. S. El'yanov; G. I. Likhtenshtein; M. G. Gonikberg; A. P. Purmal'

The effect of high pressure on the rate of decomposition of H₂O₂ by liver catalase

Yu M. Azizov, B. S. El'yanov, G. I. Likhtenshtein, M. G. Gonikberg, A. P. Purmal'

Research output: Contribution to journal › Article › peer-review

Abstract

A technique has been worked out for investigating rapid reactions in competitive conditions under pressure. We have studied the effect of pressure up to 1000 atm on the rate of decomposition of H₂O₂ by catalase. It has been found that with increase in pressure the reaction is slowed down, the effective volumetric effect of activation at atmospheric pressure of ΔV ̄^≠₁ is equal to +30 cm³/mole. It is concluded that the value for ΔV ̄^≠₁ found is due to the difference in the structure of the apoenzyme in the transitional and initial state. In the transitional state the protein has a more openwork and at the same time more rigid structure.

Original language	English
Pages (from-to)	1128-1136
Number of pages	9
Journal	Biophysics (Russian Federation)
Volume	13
Issue number	6
State	Published - 1 Dec 1968
Externally published	Yes

ASJC Scopus subject areas

Biophysics

Cite this

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title = "The effect of high pressure on the rate of decomposition of H2O2 by liver catalase",

abstract = "A technique has been worked out for investigating rapid reactions in competitive conditions under pressure. We have studied the effect of pressure up to 1000 atm on the rate of decomposition of H2O2 by catalase. It has been found that with increase in pressure the reaction is slowed down, the effective volumetric effect of activation at atmospheric pressure of ΔV{\= }≠1 is equal to +30 cm3/mole. It is concluded that the value for ΔV{\= }≠1 found is due to the difference in the structure of the apoenzyme in the transitional and initial state. In the transitional state the protein has a more openwork and at the same time more rigid structure.",

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AU - El'yanov, B. S.

AU - Likhtenshtein, G. I.

AU - Gonikberg, M. G.

AU - Purmal', A. P.

PY - 1968/12/1

Y1 - 1968/12/1

N2 - A technique has been worked out for investigating rapid reactions in competitive conditions under pressure. We have studied the effect of pressure up to 1000 atm on the rate of decomposition of H2O2 by catalase. It has been found that with increase in pressure the reaction is slowed down, the effective volumetric effect of activation at atmospheric pressure of ΔV ̄≠1 is equal to +30 cm3/mole. It is concluded that the value for ΔV ̄≠1 found is due to the difference in the structure of the apoenzyme in the transitional and initial state. In the transitional state the protein has a more openwork and at the same time more rigid structure.

AB - A technique has been worked out for investigating rapid reactions in competitive conditions under pressure. We have studied the effect of pressure up to 1000 atm on the rate of decomposition of H2O2 by catalase. It has been found that with increase in pressure the reaction is slowed down, the effective volumetric effect of activation at atmospheric pressure of ΔV ̄≠1 is equal to +30 cm3/mole. It is concluded that the value for ΔV ̄≠1 found is due to the difference in the structure of the apoenzyme in the transitional and initial state. In the transitional state the protein has a more openwork and at the same time more rigid structure.

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JO - Biophysics (Russian Federation)

JF - Biophysics (Russian Federation)

IS - 6

ER -

The effect of high pressure on the rate of decomposition of H₂O₂ by liver catalase

Abstract

ASJC Scopus subject areas

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