The effect of hyoscine n butylbromide on exocrine pancreatic secretion

H. S. Odes, C. A. Helman, G. O. Barbezat, S. Bank

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Ten adult men who underwent two successive pancreatic function tests in tandem received hyoscine-N-butylbromide intravenously before the second test. The drug inhibited secretin-stimulated protein, trypsin and amylase secretion and increased the bicarbonate concentration in the pancreatic juice. It is important to take these findings into account when interpreting the results of pure pancreatic juice collections taken during retrograde endoscopic pancreatography if the drug has been used as a duodenal relaxant.

Original languageEnglish
Pages (from-to)17-19
Number of pages3
JournalSouth African Medical Journal
Issue number1
StatePublished - 1 Dec 1977
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine


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