The effect of hysterectomy on survival of patients with borderline ovarian tumors

Joseph Menczer; Angela Chetrit; Siegal Sadetzki; Shmuel Anderman; Marco Alteras; Shaul Anteby; Jack Atad; Amiram Avni; Amiram Bar-Am; Dan Beck; Uziel Beller; Gilad Ben-Baruch; Yehuda Ben-David; Izhar Ben-Shlomo; Haim Biran; Moshe Ben Ami; Shlomit Cohen; Shulamit Cohen; Ram Dgani; Yehudit Fishler; Ami Fishman; Eitan Friedman; Ofer Gemer; Ruth Gershoni; Reuvit Halperin; Galit Hirsh-Yechezkel; David Idelman; Rafael Katan; Yuri Kopilovic; Efrat Lahad; Liat Lerner-Geva; Hanoch Levavi; Tally Levy; Albert Levit; Beatriz Lifschitz-Mercer; Flora Lubin; Zohar Leviatan; Jacob Marcovich; Baruch Modan; Hedva Nitzan; Moshe Oetinger; Tamar Perez; Benjamin Piura; David Schneider; Mariana Shteiner; Zion Tal; Chaim Yaffe; Ilana Yanai; Shifra Zohar

doi:10.1016/j.ygyno.2012.02.017

The effect of hysterectomy on survival of patients with borderline ovarian tumors

Joseph Menczer, Angela Chetrit, Siegal Sadetzki, Shmuel Anderman, Marco Alteras, Shaul Anteby, Jack Atad, Amiram Avni, Amiram Bar-Am, Dan Beck, Uziel Beller, Gilad Ben-Baruch, Yehuda Ben-David, Izhar Ben-Shlomo, Haim Biran, Moshe Ben Ami, Shlomit Cohen, Shulamit Cohen, Ram Dgani, Yehudit FishlerAmi Fishman, Eitan Friedman, Ofer Gemer, Ruth Gershoni, Reuvit Halperin, Galit Hirsh-Yechezkel, David Idelman, Rafael Katan, Yuri Kopilovic, Efrat Lahad, Liat Lerner-Geva, Hanoch Levavi, Tally Levy, Albert Levit, Beatriz Lifschitz-Mercer, Flora Lubin, Zohar Leviatan, Jacob Marcovich, Baruch Modan, Hedva Nitzan, Moshe Oetinger, Tamar Perez, Benjamin Piura, David Schneider, Mariana Shteiner, Zion Tal, Chaim Yaffe, Ilana Yanai, Shifra Zohar

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Objective: The classically recommended surgical treatment of borderline ovarian tumors (BOTs) includes hysterectomy in addition to bilateral adnexectomy. Possible reasons for hysterectomy might be a high frequency of uterine involvement and its favorable effect on survival. The purpose of the present study was to assess the frequency of uterine involvement in patients with BOTs and the effect of hysterectomy on survival. Methods: All incident cases of histological confirmed BOTs diagnosed in Israeli Jewish women between March 1 1994 and June 30 1999, were identified. Clinical and pathological characteristics were abstracted from medical records. Patients with tumors grossly confined to the ovaries (apparently stage I) were considered to have had surgical staging when at least hysterectomy, bilateral salpingooophorectomy, omentectomy and pelvic lymph node sampling were done. Results: The study group comprised 225 patients. Hysterectomy was performed in 147 (65.31%) patients and uterine involvement was present in only 3 (2.0%) of them. The 13 year survival of the total group of patients was 85.8% and of those in apparent stage I, 88.5%. Among patients with tumors apparently confined to the ovaries, no significant survival difference was observed between unstaged and surgically staged patients. There was also no survival difference between the overall staged and unstaged patients and between patients in stages II-III who did and did not undergo hysterectomy. Conclusions: Our data indicate that the rate of uterine involvement in BOT is low and that hysterectomy does not favorably affect survival. The necessity of hysterectomy in BOT patients is questioned.

Original language	English
Pages (from-to)	372-375
Number of pages	4
Journal	Gynecologic Oncology
Volume	125
Issue number	2
DOIs	https://doi.org/10.1016/j.ygyno.2012.02.017
State	Published - 1 May 2012

Keywords

Borderline ovarian tumors
Effect of hysterectomy on survival
Uterine involvement

ASJC Scopus subject areas

Oncology
Obstetrics and Gynecology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.ygyno.2012.02.017

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Menczer, J., Chetrit, A., Sadetzki, S., Anderman, S., Alteras, M., Anteby, S., Atad, J., Avni, A., Bar-Am, A., Beck, D., Beller, U., Ben-Baruch, G., Ben-David, Y., Ben-Shlomo, I., Biran, H., Ami, M. B., Cohen, S., Cohen, S., Dgani, R., ... Zohar, S. (2012). The effect of hysterectomy on survival of patients with borderline ovarian tumors. Gynecologic Oncology, 125(2), 372-375. https://doi.org/10.1016/j.ygyno.2012.02.017

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title = "The effect of hysterectomy on survival of patients with borderline ovarian tumors",

abstract = "Objective: The classically recommended surgical treatment of borderline ovarian tumors (BOTs) includes hysterectomy in addition to bilateral adnexectomy. Possible reasons for hysterectomy might be a high frequency of uterine involvement and its favorable effect on survival. The purpose of the present study was to assess the frequency of uterine involvement in patients with BOTs and the effect of hysterectomy on survival. Methods: All incident cases of histological confirmed BOTs diagnosed in Israeli Jewish women between March 1 1994 and June 30 1999, were identified. Clinical and pathological characteristics were abstracted from medical records. Patients with tumors grossly confined to the ovaries (apparently stage I) were considered to have had surgical staging when at least hysterectomy, bilateral salpingooophorectomy, omentectomy and pelvic lymph node sampling were done. Results: The study group comprised 225 patients. Hysterectomy was performed in 147 (65.31%) patients and uterine involvement was present in only 3 (2.0%) of them. The 13 year survival of the total group of patients was 85.8% and of those in apparent stage I, 88.5%. Among patients with tumors apparently confined to the ovaries, no significant survival difference was observed between unstaged and surgically staged patients. There was also no survival difference between the overall staged and unstaged patients and between patients in stages II-III who did and did not undergo hysterectomy. Conclusions: Our data indicate that the rate of uterine involvement in BOT is low and that hysterectomy does not favorably affect survival. The necessity of hysterectomy in BOT patients is questioned.",

keywords = "Borderline ovarian tumors, Effect of hysterectomy on survival, Uterine involvement",

author = "Joseph Menczer and Angela Chetrit and Siegal Sadetzki and Shmuel Anderman and Marco Alteras and Shaul Anteby and Jack Atad and Amiram Avni and Amiram Bar-Am and Dan Beck and Uziel Beller and Gilad Ben-Baruch and Yehuda Ben-David and Izhar Ben-Shlomo and Haim Biran and Ami, {Moshe Ben} and Shlomit Cohen and Shulamit Cohen and Ram Dgani and Yehudit Fishler and Ami Fishman and Eitan Friedman and Ofer Gemer and Ruth Gershoni and Reuvit Halperin and Galit Hirsh-Yechezkel and David Idelman and Rafael Katan and Yuri Kopilovic and Efrat Lahad and Liat Lerner-Geva and Hanoch Levavi and Tally Levy and Albert Levit and Beatriz Lifschitz-Mercer and Flora Lubin and Zohar Leviatan and Jacob Marcovich and Baruch Modan and Hedva Nitzan and Moshe Oetinger and Tamar Perez and Benjamin Piura and David Schneider and Mariana Shteiner and Zion Tal and Chaim Yaffe and Ilana Yanai and Shifra Zohar",

year = "2012",

month = may,

day = "1",

doi = "10.1016/j.ygyno.2012.02.017",

language = "English",

volume = "125",

pages = "372--375",

journal = "Gynecologic Oncology",

issn = "0090-8258",

publisher = "Academic Press Inc.",

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Menczer, J, Chetrit, A, Sadetzki, S, Anderman, S, Alteras, M, Anteby, S, Atad, J, Avni, A, Bar-Am, A, Beck, D, Beller, U, Ben-Baruch, G, Ben-David, Y, Ben-Shlomo, I, Biran, H, Ami, MB, Cohen, S, Cohen, S, Dgani, R, Fishler, Y, Fishman, A, Friedman, E, Gemer, O, Gershoni, R, Halperin, R, Hirsh-Yechezkel, G, Idelman, D, Katan, R, Kopilovic, Y, Lahad, E, Lerner-Geva, L, Levavi, H, Levy, T, Levit, A, Lifschitz-Mercer, B, Lubin, F, Leviatan, Z, Marcovich, J, Modan, B, Nitzan, H, Oetinger, M, Perez, T, Piura, B, Schneider, D, Shteiner, M, Tal, Z, Yaffe, C, Yanai, I & Zohar, S 2012, 'The effect of hysterectomy on survival of patients with borderline ovarian tumors', Gynecologic Oncology, vol. 125, no. 2, pp. 372-375. https://doi.org/10.1016/j.ygyno.2012.02.017

TY - JOUR

T1 - The effect of hysterectomy on survival of patients with borderline ovarian tumors

AU - Menczer, Joseph

AU - Chetrit, Angela

AU - Sadetzki, Siegal

AU - Anderman, Shmuel

AU - Alteras, Marco

AU - Anteby, Shaul

AU - Atad, Jack

AU - Avni, Amiram

AU - Bar-Am, Amiram

AU - Beck, Dan

AU - Beller, Uziel

AU - Ben-Baruch, Gilad

AU - Ben-David, Yehuda

AU - Ben-Shlomo, Izhar

AU - Biran, Haim

AU - Ami, Moshe Ben

AU - Cohen, Shlomit

AU - Cohen, Shulamit

AU - Dgani, Ram

AU - Fishler, Yehudit

AU - Fishman, Ami

AU - Friedman, Eitan

AU - Gemer, Ofer

AU - Gershoni, Ruth

AU - Halperin, Reuvit

AU - Hirsh-Yechezkel, Galit

AU - Idelman, David

AU - Katan, Rafael

AU - Kopilovic, Yuri

AU - Lahad, Efrat

AU - Lerner-Geva, Liat

AU - Levavi, Hanoch

AU - Levy, Tally

AU - Levit, Albert

AU - Lifschitz-Mercer, Beatriz

AU - Lubin, Flora

AU - Leviatan, Zohar

AU - Marcovich, Jacob

AU - Modan, Baruch

AU - Nitzan, Hedva

AU - Oetinger, Moshe

AU - Perez, Tamar

AU - Piura, Benjamin

AU - Schneider, David

AU - Shteiner, Mariana

AU - Tal, Zion

AU - Yaffe, Chaim

AU - Yanai, Ilana

AU - Zohar, Shifra

PY - 2012/5/1

Y1 - 2012/5/1

N2 - Objective: The classically recommended surgical treatment of borderline ovarian tumors (BOTs) includes hysterectomy in addition to bilateral adnexectomy. Possible reasons for hysterectomy might be a high frequency of uterine involvement and its favorable effect on survival. The purpose of the present study was to assess the frequency of uterine involvement in patients with BOTs and the effect of hysterectomy on survival. Methods: All incident cases of histological confirmed BOTs diagnosed in Israeli Jewish women between March 1 1994 and June 30 1999, were identified. Clinical and pathological characteristics were abstracted from medical records. Patients with tumors grossly confined to the ovaries (apparently stage I) were considered to have had surgical staging when at least hysterectomy, bilateral salpingooophorectomy, omentectomy and pelvic lymph node sampling were done. Results: The study group comprised 225 patients. Hysterectomy was performed in 147 (65.31%) patients and uterine involvement was present in only 3 (2.0%) of them. The 13 year survival of the total group of patients was 85.8% and of those in apparent stage I, 88.5%. Among patients with tumors apparently confined to the ovaries, no significant survival difference was observed between unstaged and surgically staged patients. There was also no survival difference between the overall staged and unstaged patients and between patients in stages II-III who did and did not undergo hysterectomy. Conclusions: Our data indicate that the rate of uterine involvement in BOT is low and that hysterectomy does not favorably affect survival. The necessity of hysterectomy in BOT patients is questioned.

AB - Objective: The classically recommended surgical treatment of borderline ovarian tumors (BOTs) includes hysterectomy in addition to bilateral adnexectomy. Possible reasons for hysterectomy might be a high frequency of uterine involvement and its favorable effect on survival. The purpose of the present study was to assess the frequency of uterine involvement in patients with BOTs and the effect of hysterectomy on survival. Methods: All incident cases of histological confirmed BOTs diagnosed in Israeli Jewish women between March 1 1994 and June 30 1999, were identified. Clinical and pathological characteristics were abstracted from medical records. Patients with tumors grossly confined to the ovaries (apparently stage I) were considered to have had surgical staging when at least hysterectomy, bilateral salpingooophorectomy, omentectomy and pelvic lymph node sampling were done. Results: The study group comprised 225 patients. Hysterectomy was performed in 147 (65.31%) patients and uterine involvement was present in only 3 (2.0%) of them. The 13 year survival of the total group of patients was 85.8% and of those in apparent stage I, 88.5%. Among patients with tumors apparently confined to the ovaries, no significant survival difference was observed between unstaged and surgically staged patients. There was also no survival difference between the overall staged and unstaged patients and between patients in stages II-III who did and did not undergo hysterectomy. Conclusions: Our data indicate that the rate of uterine involvement in BOT is low and that hysterectomy does not favorably affect survival. The necessity of hysterectomy in BOT patients is questioned.

KW - Borderline ovarian tumors

KW - Effect of hysterectomy on survival

KW - Uterine involvement

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U2 - 10.1016/j.ygyno.2012.02.017

DO - 10.1016/j.ygyno.2012.02.017

M3 - Article

AN - SCOPUS:84859587950

SN - 0090-8258

VL - 125

SP - 372

EP - 375

JO - Gynecologic Oncology

JF - Gynecologic Oncology

IS - 2

ER -

The effect of hysterectomy on survival of patients with borderline ovarian tumors

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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