The effect of obstructive sleep apnea on morbidity and health care utilization of middle-aged and older adults

Ariel Tarasiuk, Sari Greenberg-Dotan, Tzahit Simon-Tuval, Arie Oksenberg, Haim Reuveni

Research output: Contribution to journalArticlepeer-review

72 Scopus citations


OBJECTIVES: To determine whether elderly subjects with obstructive sleep apnea (OSA) had different morbidity and health care utilization than elderly subjects without OSA and middle-aged patients with OSA 2 years before diagnosis. DESIGN: Case-control study between January 2001 and April 2003. SETTING: Two sleep-wake disorders centers. PARTICIPANTS: One hundred fifty-eight elderly and 1,166 middle-aged (aged 67-89 and 40-64, respectively) patients with OSA were matched 1:1 with healthy controls according to age, sex, geographic area, and primary physician. MEASUREMENTS: Polysomnography, medical diagnoses, and healthcare utilization. RESULTS: Healthcare costs 2 years before diagnosis were more than 1.8 times as high for elderly and middle-aged patients with OSA as for controls (P<.001). Expenditures of elderly patients with OSA were 1.9 times as high as for middle-aged patients with OSA (P<.001). Multiple logistic regression analysis (adjusting for age, body mass index, and apnea hypopnea index) revealed that cardiovascular disease (CVD) (odds ratio (OR)=4.1, 95% confidence interval (CI)=1.8-9.3) and use of psychoactive drugs (OR=3.8, 95% CI=1.5-10.1) are independent determinants for the top-third most-costly elderly patients with OSA. CONCLUSION: Elderly patients with OSA have high healthcare utilization because of CVD morbidity and use of psychoactive medications. Therefore, OSA has clinical significance in elderly people.

Original languageEnglish
Pages (from-to)247-254
Number of pages8
JournalJournal of the American Geriatrics Society
Issue number2
StatePublished - 1 Feb 2008
Externally publishedYes


  • Elderly
  • Heathcare utilization
  • Obstructive sleep apnea


Dive into the research topics of 'The effect of obstructive sleep apnea on morbidity and health care utilization of middle-aged and older adults'. Together they form a unique fingerprint.

Cite this